Browse our latest Neuroscience articles

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    1. Developmental Biology
    2. Neuroscience

    Neurotransmitter Identity: A question of lineage

    Sonia Sen
    In the ventral nerve cord of fruit flies, neurons from the same hemilineage use the same neurotransmitter.
    Version of Record
    Insight
    1. Neuroscience

    Mapping the transcriptional diversity of genetically and anatomically defined cell populations in the mouse brain

    Ken Sugino, Erin Clark ... Sacha B Nelson
    A transcriptome dataset of nearly 200 genetically identified mouse neuronal cell types revealed that short low-noise homeobox transcription factors and long neuronal effector genes best distinguish neuronal cell types.
    1. Developmental Biology
    2. Neuroscience

    Regulation of subcellular dendritic synapse specificity by axon guidance cues

    Emily C Sales, Emily L Heckman ... Chris Q Doe
    Axon guidance cues restrict sensory neuron synapse formation to a subset of equally acceptable interneuronal dendritic arbors during Drosophila locomotor circuit assembly.
    1. Neuroscience

    Parallel visual circuitry in a basal chordate

    Matthew J Kourakis, Cezar Borba ... William C Smith
    The ascidian Ciona integrates visual information from two photoreceptor types through convergent excitatory and disinhibitory circuits, thereby evoking swim behaviors.
    1. Neuroscience

    Cerebellar Purkinje cells control eye movements with a rapid rate code that is invariant to spike irregularity

    Hannah L Payne, Ranran L French ... Jennifer L Raymond
    Patterned optogenetic stimulation and analysis of neural activity provide convergent evidence that cerebellar Purkinje cells drive eye movements with a rapid rate code, without an additional contribution of spike irregularity.
    1. Neuroscience

    A valve-like mechanism controls desensitization of functional mammalian isoforms of acid-sensing ion channels

    Yangyu Wu, Zhuyuan Chen, Cecilia M Canessa
    Three residues work together as a valve-like mechanism to control desensitization from pre-open and open states in the ion channels ASIC1a, ASIC2a, and ASIC3.
    1. Cell Biology
    2. Neuroscience

    Structural plasticity of actin-spectrin membrane skeleton and functional role of actin and spectrin in axon degeneration

    Guiping Wang, David J Simon ... Xiaowei Zhuang
    Neurotrophin deprivation leads to rapid caspase-independent disassembly of the actin-spectrin-based membrane skeleton and spectrin-dependent retrograde signaling in axon degeneration.
    1. Neuroscience

    Dual separable feedback systems govern firing rate homeostasis

    Yelena Kulik, Ryan Jones ... Graeme W Davis
    A new mechanistic framework for considering the homeostatic control of neuronal firing rates is presented.
    1. Neuroscience

    State-dependent geometry of population activity in rat auditory cortex

    Dmitry Kobak, Jose L Pardo-Vazquez ... Alfonso Renart
    Representation of sound lateralisation and intensity by neural population in the rat auditory cortex strongly depends on the brain state suggesting that the neural tuning to lateralisation is not hard-wired.
    1. Neuroscience

    Genetic dissection of the different roles of hypothalamic kisspeptin neurons in regulating female reproduction

    Luhong Wang, Charlotte Vanacker ... Suzanne M Moenter
    Estradiol regulates the pre-ovulatory luteinizing hormone surge through hypothalamic anteroventral periventricular kisspeptin neurons and maintains reproductive cyclicity through arcuate kisspeptin neurons in an activational manner.