Browse our latest Neuroscience articles

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    1. Neuroscience

    Functional MRI: Making connections in the brain

    Alex TL Leong, Ed X Wu
    Simultaneous measurements of neuronal activity and fMRI signals in the rat brain have shed new light on the origins of resting-state fMRI connectivity networks.
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    1. Neuroscience

    A double-sided microscope to realize whole-ganglion imaging of membrane potential in the medicinal leech

    Yusuke Tomina, Daniel A Wagenaar
    For the first time, action potentials and subthreshold postsynaptic potentials of almost all individual identifiable neurons within a functional unit of the leech nervous system were simultaneously imaged during sensory processing and behavioral generation.
    1. Neuroscience

    Parvalbumin-positive interneurons mediate neocortical-hippocampal interactions that are necessary for memory consolidation

    Frances Xia, Blake A Richards ... Paul W Frankland
    Electrophysiological and behavioural experiments reveal that parvalbumin interneuron-mediated increases in neocortical-hippocampal interactions are necessary for successful memory consolidation.
    1. Neuroscience

    Striatal adenosine A2A receptor neurons control active-period sleep via parvalbumin neurons in external globus pallidus

    Xiang-Shan Yuan, Lu Wang ... Zhi-Li Huang
    Rostral and central striatum controls slow-wave sleep during active phase in mice.
    1. Neuroscience

    Theta-burst microstimulation in the human entorhinal area improves memory specificity

    Ali S Titiz, Michael R H Hill ... Itzhak Fried
    Precisely targeted, low current brain microstimulation is sufficient to enhance human memory.
    1. Neuroscience

    Neural and computational processes underlying dynamic changes in self-esteem

    Geert-Jan Will, Robb B Rutledge ... Raymond J Dolan
    Self-esteem, the value that people ascribe to the self, is represented in the ventromedial prefrontal cortex and dynamically updated when people learn how others value them.
    1. Neuroscience

    Small conductance Ca2+-activated K+ channels induce the firing pause periods during the activation of Drosophila nociceptive neurons

    Koun Onodera, Shumpei Baba ... Tadao Usui
    Drosophila nociceptive neurons convert high-intensity stimuli into characteristic fluctuations of firing rates, quiescent periods of which are regulated by hyperpolarization through small conductance Ca2+-activated K+ channels.
    1. Neuroscience

    Functional dichotomy in spinal- vs prefrontal-projecting locus coeruleus modules splits descending noradrenergic analgesia from ascending aversion and anxiety in rats

    Stefan Hirschberg, Yong Li ... Anthony E Pickering
    The locus coeruleus is organised into functional modules with subsets of noradrenergic neurones independently projecting to the spinal cord and prefrontal cortex to exert discrete, antithetical modulatory actions on a range of pain-related behaviours.
    1. Neuroscience

    Local processing in neurites of VGluT3-expressing amacrine cells differentially organizes visual information

    Jen-Chun Hsiang, Keith P Johnson ... Daniel Kerschensteiner
    Neurite arbors of VGluT3-expressing amacrine cells (VG3-ACs) process visual information locally uniformly detecting object motion while varying in contrast preferences; and in spite of extensive overlap between arbors of neighboring cells population activity in the VG3-AC plexus encodes stimulus positions with subcellular precision.
    1. Neuroscience

    Removal of inhibition uncovers latent movement potential during preparation

    Uday K Jagadisan, Neeraj J Gandhi
    Non-invasive disinhibition of the oculomotor system shows that ongoing preparatory activity in the superior colliculus has movement-generating potential and need not rise to threshold in order to produce a saccade.