Humans adjust the degree to which they learn from positive relative to negative outcomes as a function of how informative they estimate those outcomes to be.
Mattia Volta, Dayne A Beccano-Kelly ... Austen J Milnerwood
LRRK2 G2019S knock-in mice are a genetically faithful model that recapitulates the slow disease progression of familial PD, with initial alterations to behaviour and neurotransmission providing early pathophysiological targets for neuroprotective interventions.
Milos Radivojevic, Felix Franke ... Douglas J Bakkum
A method was developed to non-invasively and simultaneously track individual action-potentials propagating across multiple branches of identified neurons in neocortical cultures.
Esteban J Beckwith, Quentin Geissmann ... Giorgio F Gilestro
Sexual arousal, exposure to aphrodisiac pheromones, or mere activation of peripheral pheromone-sensing neurons can modulate sleep homeostasis and are able to counteract the effects of sleep deprivation in Drosophila.
Sachiko Murase, Crystal L Lantz, Elizabeth M Quinlan
Light reintroduction (LRx) after dark exposure reactivates structural and functional plasticity in the adult mouse visual cortex by increasing the activity of MMP-9 at thalamo-cortical synapses.
Wojciech K Zajkowski, Malgorzata Kossut, Robert C Wilson
Disruption of right frontopolar cortex with transcranial magnetic stimulation causes selective deficits in exploratory behavior suggesting that different strategies of exploration are implemented by different neural circuits.
Many disorders are characterized by underlying abnormalities in network connectivity which, though difficult to address with explicit training procedures, can be directly targeted through covert neurofeedback.