Browse our latest Neuroscience articles

Page 485 of 644
    1. Neuroscience

    Learning: How the cerebellum learns to build a sequence

    Reza Shadmehr
    Rabbits can learn the biological analogue of a simple recursive function by relying only on the neurons of the cerebellum.
    Version of Record
    Insight
    1. Neuroscience

    NPAS4 recruits CCK basket cell synapses and enhances cannabinoid-sensitive inhibition in the mouse hippocampus

    Andrea L Hartzell, Kelly M Martyniuk ... Brenda L Bloodgood
    Behaviorally-driven expression of the immediate early gene transcription factor NPAS4 changes local circuit connectivity and short-term plasticity by selectively recruiting CCK basket cell synapses to pyramidal neuron somas.
    1. Neuroscience

    Cerebellar involvement in an evidence-accumulation decision-making task

    Ben Deverett, Sue Ann Koay ... Samuel S-H Wang
    In a new evidence-accumulation decision-making task, activity of the lateral posterior cerebellum is necessary for accurate performance, and somatic and dendritic activity in Purkinje cells contains choice/evidence and error-related information.
    1. Neuroscience

    Estrogenic-dependent glutamatergic neurotransmission from kisspeptin neurons governs feeding circuits in females

    Jian Qiu, Heidi M Rivera ... Oline K Rønnekleiv
    Estrogen increases hypothalamic arcuate kisspeptin neuronal excitability and glutamate release to coordinate autonomic functions for maximizing reproductive success.
    1. Neuroscience

    Arcuate nucleus and lateral hypothalamic CART neurons in the mouse brain exert opposing effects on energy expenditure

    Aitak Farzi, Jackie Lau ... Herbert Herzog
    CART exerts differential metabolic effects in response to activation of neurons of the Arc, where CART suppresses energy expenditure, while it enforces the reward characteristics of the LHA.
    1. Neuroscience

    Elementary sensory-motor transformations underlying olfactory navigation in walking fruit-flies

    Efrén Álvarez-Salvado, Angela M Licata ... Katherine I Nagel
    A high-throughput behavioral paradigm and computational modeling are used to decompose olfactory navigation in walking Drosophila melanogaster into a set of quantitative relationships between sensory input and motor output.
    1. Neuroscience

    Functional heterogeneity within the rodent lateral orbitofrontal cortex dissociates outcome devaluation and reversal learning deficits

    Marios C Panayi, Simon Killcross
    The rodent orbitofrontal cortex makes functionally distinct contributions to flexible behavioural control, even within a single putative orbitofrontal subregion, which has important implications for establishing homology between rodent and primate orbitofrontal cortex.
    1. Neuroscience

    MDN brain descending neurons coordinately activate backward and inhibit forward locomotion

    Arnaldo Carreira-Rosario, Aref Arzan Zarin ... Chris Q Doe
    A brain descending interneuron can coordinate a switch between two antagonistic behaviors (forward and backward locomotions).
    1. Neuroscience
    2. Structural Biology and Molecular Biophysics

    Single-particle cryo-EM structure of a voltage-activated potassium channel in lipid nanodiscs

    Doreen Matthies, Chanhyung Bae ... Kenton Jon Swartz
    The structure of a voltage-activated potassium channel in lipid nanodiscs solved using cryo-electron microscopy is similar to previous X-ray structures, and provides insights into the mechanism of C-type inactivation.
    1. Neuroscience
    2. Structural Biology and Molecular Biophysics

    Cryo-EM structure of alpha-synuclein fibrils

    Ricardo Guerrero-Ferreira, Nicholas MI Taylor ... Henning Stahlberg
    The alpha-synuclein fibril structure reported here buries residues 50-57 at the interface between its two protofilaments, suggesting that familial Parkinson's disease associated mutations in these residues lead to a structure not compatible with the one presented here.