Browse our latest Neuroscience articles

Page 485 of 599
    1. Neuroscience

    A spiral attractor network drives rhythmic locomotion

    Angela M Bruno, William N Frost, Mark D Humphries
    The neural population of the Aplysia's pedal ganglion are a low-dimensional spiral attractor, and the parameters of the attractor directly define the properties of the Aplysia's escape locomotion behaviour.
    1. Neuroscience

    Task-dependent recurrent dynamics in visual cortex

    Satohiro Tajima, Kowa Koida ... Hidehiko Komatsu
    A decoding-based, state-space reconstruction reveals that neurons in macaque IT cortex change the structure of their collective attractor dynamics depending on task contexts.
    1. Neuroscience

    Physiological and pathophysiological control of synaptic GluN2B-NMDA receptors by the C-terminal domain of amyloid precursor protein

    Paula A Pousinha, Xavier Mouska ... Hélène Marie
    The APP intracellular domain (AICD) physiologically regulates synaptic GluN2B-containing NMDA receptor current, a process that could contribute to pathological Alzheimer's disease-related synaptic failure upon increase of AICD levels in adult neurons.
    1. Neuroscience

    Pro-death NMDA receptor signaling is promoted by the GluN2B C-terminus independently of Dapk1

    Jamie McQueen, Tomás J Ryan ... Giles E Hardingham
    Excitotoxicity driven by NMDA receptor hyper-activation does not involve DAPK1-dependent events in vitro or in vivo, and previously described DAPK1-NMDAR disrupting peptides act by blocking the NMDA receptor.
    1. Cell Biology
    2. Neuroscience

    Pharmacological evidence for a metabotropic glutamate receptor heterodimer in neuronal cells

    David Moreno Delgado, Thor C Møller ... Jean-Philippe Pin
    Innovative approaches were used to identify the specific pharmacological properties of heterodimeric metabotropic glutamate receptors composed of mGlu2 and mGlu4 subunits, and reveal their existence in a neuronal cell line and in perforant path terminals.
    1. Neuroscience

    Plasticity of calcium-permeable AMPA glutamate receptors in Pro-opiomelanocortin neurons

    Shigetomo Suyama, Alexandra Ralevski ... Tamas L Horvath
    Neurons in the hypothalamus that promote satiety manifest plasticity of their response to the excitatory transmitter, glutamate, by re-organizing the composition of a specific glutamare receptor.
    1. Neuroscience

    Energy imbalance alters Ca2+ handling and excitability of POMC neurons

    Lars Paeger, Andreas Pippow ... Peter Kloppenburg
    The development of diet-dependent obesity results in the deterioration of calcium homeostasis in pro-opiomelanocortin-expressing neurons and impaired function of the same neurons.
    1. Neuroscience

    Phasic and tonic neuron ensemble codes for stimulus-environment conjunctions in the lateral entorhinal cortex

    Maryna Pilkiw, Nathan Insel ... Kaori Takehara-Nishiuchi
    Neuron populations in the lateral entorhinal cortex discriminate between memory-based contexts through both continuous "tonic" activity patterns as well as by their stimulus-evoked "phasic" responses.
    1. Neuroscience

    Complementary contributions of basolateral amygdala and orbitofrontal cortex to value learning under uncertainty

    Alexandra Stolyarova, Alicia Izquierdo
    Rat orbitofrontal cortex is required to accurately represent outcome distributions, whereas basolateral amygdala is necessary for the facilitation of learning in response to surprising events.
    1. Neuroscience

    Ciliomotor circuitry underlying whole-body coordination of ciliary activity in the Platynereis larva

    Csaba Verasztó, Nobuo Ueda ... Gáspár Jékely
    Connectomic reconstruction combined with activity imaging uncovered a rhythmically active neuronal circuit for the coordination of ciliary activity across the whole body of a marine larva.