Browse our latest Neuroscience articles

Page 491 of 603
    1. Neuroscience

    Ionic mechanisms underlying history-dependence of conduction delay in an unmyelinated axon

    Yang Zhang, Dirk Bucher, Farzan Nadim
    Conduction velocity of action potentials in unmyelinated axons depends ultimately on the gating variables of the fast voltage-gated sodium current and can be predicted from the action potential peak and trough voltages.
    1. Developmental Biology
    2. Neuroscience

    Ephrin-A/EphA specific co-adaptation as a novel mechanism in topographic axon guidance

    Felix Fiederling, Markus Weschenfelder ... Franco Weth
    A distinctive novel mechanism of ephrin-A/EphA signaling modulation in retinal growth cones ensures concurrent quantitative accuracy and adaptability of topographic hardwiring.
    1. Neuroscience

    Arid1b haploinsufficient mice reveal neuropsychiatric phenotypes and reversible causes of growth impairment

    Cemre Celen, Jen-Chieh Chuang ... Hao Zhu
    Mirroring human patients with ARID1B mutations, Arid1b haploinsufficient mice exhibited numerous neuropsychiatric defects and revealed IGF1 deficiency related growth impairment that could be ameliorated with growth hormone supplementation.
    1. Neuroscience

    The Na+/Ca2+, K+ exchanger NCKX4 is required for efficient cone-mediated vision

    Frans Vinberg, Tian Wang ... Vladimir J Kefalov
    Molecular, genetic, and functional analysis is used to show that the olfactory Na+/Ca2+, K+ exchanger NCKX4 is expressed in cone photoreceptors and is critical for the wide operating range and high temporal resolution of cone-mediated vision.
    1. Computational and Systems Biology
    2. Neuroscience

    Reciprocal regulation of ARPP-16 by PKA and MAST3 kinases provides a cAMP-regulated switch in protein phosphatase 2A inhibition

    Veronica Musante, Lu Li ... Angus C Nairn
    A complex interplay between MAST3 and PKA protein kinases and the regulatory protein ARPP-16 allows cAMP to control the activity of protein phosphatase 2A.
    1. Neuroscience

    A subset of ipRGCs regulates both maturation of the circadian clock and segregation of retinogeniculate projections in mice

    Kylie S Chew, Jordan M Renna ... Samer Hattar
    A single subpopulation of photoreceptors constitutes a shared node in the neural networks that regulate light-dependent maturation of the circadian clock and light-independent refinement of retinal ganglion cell projections to the brain.
    1. Developmental Biology
    2. Neuroscience

    The laminar organization of the Drosophila ellipsoid body is semaphorin-dependent and prevents the formation of ectopic synaptic connections

    Xiaojun Xie, Masashi Tabuchi ... Alex L Kolodkin
    The organization of layered/laminated axon projections in specific regions of the fruitfly central brain is regulated by short-range repulsive guidance and is critical for local inhibitory circuit formation and function.
    1. Neuroscience

    Dye-enhanced visualization of rat whiskers for behavioral studies

    Jacopo Rigosa, Alessandro Lucantonio ... Mathew E Diamond
    A simple fluorescent dye method allows visualization of whiskers, facilitating studies of rodent tactile behavior.
    1. Biochemistry and Chemical Biology
    2. Neuroscience

    Somatostatin binds to the human amyloid β peptide and favors the formation of distinct oligomers

    Hansen Wang, Lisa D Muiznieks ... Gerold Schmitt-Ulms
    The cyclic neuropeptide somatostatin binds to human Aβ1-42 through an interface that critically relies on a specific tryptophan, thereby blocking the propensity of Aβ to aggregate, a critical step in the pathobiology of Alzheimer's disease.
    1. Ecology
    2. Neuroscience

    Individual recognition and the ‘face inversion effect’ in medaka fish (Oryzias latipes)

    Mu-Yun Wang, Hideaki Takeuchi
    Medaka fish were able to use faces for individual recognition, and were slower to recognise inverted faces but not inverted non-face shapes.