Browse our latest Neuroscience articles

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    1. Neuroscience

    Cognitive regulation alters social and dietary choice by changing attribute representations in domain-general and domain-specific brain circuits

    Anita Tusche, Cendri A Hutcherson
    Regulatory success operates by goal-consistent increases and decreases of distinct attribute representations in generic neural hubs and in domain-specific brain regions, explaining when and why regulatory success generalizes across domains and contexts.
    1. Neuroscience

    Prediction error induced motor contagions in human behaviors

    Tsuyoshi Ikegami, Gowrishankar Ganesh ... Hiroki Nakamoto
    A new type of implicit effects on one's actions induced by prediction errors during action observation is discovered.
    1. Neuroscience
    2. Structural Biology and Molecular Biophysics

    An NMDAR positive and negative allosteric modulator series share a binding site and are interconverted by methyl groups

    Riley Perszyk, Brooke M Katzman ... Stephen F Traynelis
    A series of novel compounds selective for N-methyl-D-aspartate-type glutamate receptor includes positive and negative allosteric modulators that act at the same site, show use-dependence, increase agonist potency, and have differential activity based on the agonist concentration.
    1. Neuroscience
    2. Structural Biology and Molecular Biophysics

    Pharmacology: A Swiss army knife for targeting receptors

    Johansen B Amin, Lonnie P Wollmuth
    A compound can change the activity of NMDA receptors in some regions of a synapse without affecting those in other regions.
    Version of Record
    Insight
    1. Neuroscience

    Autistic traits, but not schizotypy, predict increased weighting of sensory information in Bayesian visual integration

    Povilas Karvelis, Aaron R Seitz ... Peggy Seriès
    Autistic traits are associated with weaker influence of prior expectations in visual perception, which is due to more precise sensory representations.
    1. Neuroscience

    Perception of social interaction compresses subjective duration in an oxytocin-dependent manner

    Rui Liu, Xiangyong Yuan ... Wen Zhou
    The subjective time of social interactions reflects one's autistic-like tendency and is critically mediated by oxytocin, indicating that time perception is ingrained with personality traits, which likely have neuroendocrine origins as per previous research.
    1. Neuroscience

    A homozygous loss-of-function CAMK2A mutation causes growth delay, frequent seizures and severe intellectual disability

    Poh Hui Chia, Franklin Lei Zhong ... Bruno Reversade
    A biallelic missense mutation in the highly conserved, neuron-specific kinase CAMK2A abrogates holoenzyme assembly and causes a new inherited neurodevelopmental disease.
    1. Computational and Systems Biology
    2. Neuroscience

    Post-decision biases reveal a self-consistency principle in perceptual inference

    Long Luu, Alan A Stocker
    Humans are biased in their assessment of sensory information by their own preceding categorical judgment in an attempt to remain self-consistent.
    1. Neuroscience

    Optical detection of three modes of endocytosis at hippocampal synapses

    Natali L Chanaday, Ege T Kavalali
    Single synaptic vesicle imaging shows that kinetically distinct endocytic pathways are differentially regulated by calcium and temperature, and influence the fidelity of synaptic vesicle protein retrieval.
    1. Neuroscience

    Combinatorial programming of human neuronal progenitors using magnetically-guided stoichiometric mRNA delivery

    Sayyed M Azimi, Steven D Sheridan ... Mehmet Fatih Yanik
    A technology allows rapid screening of vast numbers of transcriptional factor combinatorials on stem cell programming.