Browse our latest Neuroscience articles

Page 498 of 603
    1. Neuroscience

    Calcium dynamics regulating the timing of decision-making in C. elegans

    Yuki Tanimoto, Akiko Yamazoe-Umemoto ... Koutarou D Kimura
    A series of quantitative behavioural and opto-physiological analyses using a novel robot microscope system reveals that C. elegans computes the time-differential and time-integral of sensory information for decision-making during olfactory navigation.
    1. Neuroscience

    mTORC1 in AGRP neurons integrates exteroceptive and interoceptive food-related cues in the modulation of adaptive energy expenditure in mice

    Luke K Burke, Tamana Darwish ... Clémence Blouet
    AGRP neurons integrate environmental food-related cues with internal metabolic signals to modulate interscapular brown adipose tissue thermogenesis and energy expenditure, at least in part, via mTORC1 signalling.
    1. Neuroscience

    Optocontrol of glutamate receptor activity by single side-chain photoisomerization

    Viktoria Klippenstein, Christian Hoppmann ... Pierre Paoletti
    Introduction of single photoswitchable unnatural amino acid into a neuronal receptor provides reversible, rapid and robust control of its activity by light, representing an important contribution to the fast expanding field of optopharmacology.
    1. Structural Biology and Molecular Biophysics
    2. Neuroscience

    Molecular mechanism of voltage-dependent potentiation of KCNH potassium channels

    Gucan Dai, William N Zagotta
    A powerful new fluorescence approach elucidates the structural mechanism for a specialized ion channel behavior important for cardiac and neuronal excitability.
    1. Neuroscience

    Axons: The cost of communication in the brain

    Brian A MacVicar, Leigh Wicki-Stordeur, Louis-Philippe Bernier
    Imaging ATP in axons reveals that they rely on glucose from the blood and lactate produced by glial cells as sources of energy.
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    1. Neuroscience

    Angular velocity integration in a fly heading circuit

    Daniel Turner-Evans, Stephanie Wegener ... Vivek Jayaraman
    A distinctive recurrent network motif in the Drosophila central brain enables neurons that encode angular velocity to shift population activity in compass neurons, thereby updating their heading representation whenever the fly turns.
    1. Neuroscience

    Wiring variations that enable and constrain neural computation in a sensory microcircuit

    William F Tobin, Rachel I Wilson, Wei-Chung Allen Lee
    Systematic and coordinated variations in morphology and connectivity can structurally tune a microcircuit's computation but non-systematic variably also exists, imparting "connection noise" that potentially limits processing performance.
    1. Developmental Biology
    2. Neuroscience

    USP5/Leon deubiquitinase confines postsynaptic growth by maintaining ubiquitin homeostasis through Ubiquilin

    Chien-Hsiang Wang, Yi-Chun Huang ... Cheng-Ting Chien
    Maintenance of ubiquitin homeostasis is essential for proper control of the size of postsynaptic density and the growth of specialized membrane structure.
    1. Neuroscience

    Complementary codes for odor identity and intensity in olfactory cortex

    Kevin A Bolding, Kevin M Franks
    Different features of an odor can be represented in mouse olfactory cortex using the particular ensemble of responsive neurons to represent odor identity and the synchrony of the ensemble activity to represent odor intensity.
    1. Neuroscience

    Odor identity coding by distributed ensembles of neurons in the mouse olfactory cortex

    Benjamin Roland, Thomas Deneux ... Alexander Fleischmann
    In vivo calcium imaging reveals how odor identity is encoded in the activity of large, distributed ensembles of olfactory cortex neurons in mice.