Browse our latest Neuroscience articles

Computational simulations and mathematical derivations reveal why the response of neural populations to external modulation is sometimes reversed with respect to what intuition would lead to believe in cortical circuits with multiple types of inhibitory neurons.

Keratinocytes are critical for normal innocuous and noxious touch through their mechanically evoked ATP release and subsequent signaling to P2X4 channels on sensory neurons.

The VTA-mOT DAergic pathway mediates a variety of naturalistic reward processes and different types of preferences including odor-preference.

The microenvironment of brain tumors can be modulated by in vivo conditions that change the brain levels of BDNF and IL-15, with effects on innate immune cell activation.

A screen encompassing all kinases and phosphatases reveals that PI3K-cII, PI3K-cIII and Rab11-dependent recycling endosomes comprise a novel, postsynaptic 'signaling controller' that is part of an integrated, trans-synaptic signaling system necessary for presynaptic homeostatic plasticity.

Experiments on neurons in the heart system of the leech reveal why rhythmic behaviors differ between individuals.

Population output variability in a motor control system varies across levels (CPG, motor neurons, muscles) and can be ascribed to life history differences among animals and in some cases to differences between bilaterally homologous elements.

Astrocytes impact neuronal signaling in brain dependent on status of the transcriptional repressor, Methyl CpG Binding Protein 2.

Goal-directed interaction with objects and spatial navigation are subserved by the perirhinal-lateral entorhinal networks and the postrhinal-medial entorhinal networks, respectively, with action-based functional differentiation more strongly represented in the entorhinal cortex than its upstream.

Hippocampal neurons undergo bi-stable behavior as neurites emerge, and the dominance of either state is determined by environmental mechanical properties and paxillin-associated cellular endocytic activities.