Browse our latest Neuroscience articles

Page 511 of 644
    1. Neuroscience

    HCN2 channels in the ventral tegmental area regulate behavioral responses to chronic stress

    Peng Zhong, Casey R Vickstrom ... Qing-song Liu
    HCN2 channels in the ventral tegmental area play an important role in the pathophysiology of chronic mild stress-induced behavioral deficits.
    1. Neuroscience

    Synaptic and peptidergic connectome of a neurosecretory center in the annelid brain

    Elizabeth A Williams, Csaba Verasztó ... Gáspár Jékely
    A combination of electron microscopic reconstruction and the analysis of single cell transcriptome data is used to reconstruct synaptic and peptidergic signaling networks in a neurosecretory centre.
    1. Neuroscience

    Molecular basis of fatty acid taste in Drosophila

    Ji-Eun Ahn, Yan Chen, Hubert Amrein
    Molecular-genetic, neural imaging and behavioral analyses reveal how Drosophila melanogaster sense fatty acids, important nutrient compounds, through multimeric Ionoptropic Receptors complexes.
    1. Neuroscience

    Salt-inducible kinase 3 regulates the mammalian circadian clock by destabilizing PER2 protein

    Naoto Hayasaka, Arisa Hirano ... Yoshitaka Fukada
    Salt-inducible kinase 3 (SIK3) is an essential component of the mammalian circadian clock machinery, which governs robust circadian behavioral and other rhythms by destabilization of a core clock protein PER2 in a phosphorylation-dependent manner.
    1. Neuroscience

    Representation of time interval entrained by periodic stimuli in the visual thalamus of pigeons

    Yan Yang, Qian Wang ... Qian Xiao
    The experience-dependent representation of time interval in the seconds-to-minutes range occurs as early as at the thalamic level in the brain.
    1. Neuroscience

    Eye opening differentially modulates inhibitory synaptic transmission in the developing visual cortex

    Wuqiang Guan, Jun-Wei Cao ... Yong-Chun Yu
    Our work demonstrated that eye opening differentially modulates inhibitory synaptic transmission from Sst-INs and FS-INs to excitatory neurons in the mammalian cortex.
    1. Neuroscience

    Serotonin enhances excitability and gamma frequency temporal integration in mouse prefrontal fast-spiking interneurons

    Jegath C Athilingam, Roy Ben-Shalom ... Kevin J Bender
    Serotonin changes passive membrane properties in prefrontal fast-spiking interneurons to affect not only neuronal excitability but also the temporal filtering of synaptic inputs with a preference for gamma-frequency summation.
    1. Neuroscience

    Inhibition of PIP4Kγ ameliorates the pathological effects of mutant huntingtin protein

    Ismael Al-Ramahi, Sai Srinivas Panapakkam Giridharan ... Juan Jose Marugan
    This work validates PIP4K gamma as pharmacological target to ameliorate Huntington's disease.
    1. Neuroscience

    The AMPA receptor-associated protein Shisa7 regulates hippocampal synaptic function and contextual memory

    Leanne J M Schmitz, Remco V Klaassen ... Sabine Spijker
    Shisa7 is a bona-fide AMPAR modulatory protein affecting channel kinetics of hippocampal AMPARs, and is necessary for synaptic plasticity and memory recall.
    1. Computational and Systems Biology
    2. Neuroscience

    T2N as a new tool for robust electrophysiological modeling demonstrated for mature and adult-born dentate granule cells

    Marcel Beining, Lucas Alberto Mongiat ... Peter Jedlicka
    T2N, a novel interface between Matlab, TREES toolbox and NEURON, was used to generate compartmental models that reproduce the electrophysiology of dentate granule cells over a multitude of species, experimental conditions and developmental stages.