Elizabeth A Williams, Csaba Verasztó ... Gáspár Jékely
A combination of electron microscopic reconstruction and the analysis of single cell transcriptome data is used to reconstruct synaptic and peptidergic signaling networks in a neurosecretory centre.
Molecular-genetic, neural imaging and behavioral analyses reveal how Drosophila melanogaster sense fatty acids, important nutrient compounds, through multimeric Ionoptropic Receptors complexes.
Salt-inducible kinase 3 (SIK3) is an essential component of the mammalian circadian clock machinery, which governs robust circadian behavioral and other rhythms by destabilization of a core clock protein PER2 in a phosphorylation-dependent manner.
Our work demonstrated that eye opening differentially modulates inhibitory synaptic transmission from Sst-INs and FS-INs to excitatory neurons in the mammalian cortex.
Jegath C Athilingam, Roy Ben-Shalom ... Kevin J Bender
Serotonin changes passive membrane properties in prefrontal fast-spiking interneurons to affect not only neuronal excitability but also the temporal filtering of synaptic inputs with a preference for gamma-frequency summation.
Leanne J M Schmitz, Remco V Klaassen ... Sabine Spijker
Shisa7 is a bona-fide AMPAR modulatory protein affecting channel kinetics of hippocampal AMPARs, and is necessary for synaptic plasticity and memory recall.
Marcel Beining, Lucas Alberto Mongiat ... Peter Jedlicka
T2N, a novel interface between Matlab, TREES toolbox and NEURON, was used to generate compartmental models that reproduce the electrophysiology of dentate granule cells over a multitude of species, experimental conditions and developmental stages.