Browse our latest Neuroscience articles

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    1. Neuroscience

    Inhibition of Transient Receptor Potential Melastatin 3 ion channels by G-protein βγ subunits

    Doreen Badheka, Yevgen Yudin ... Tibor Rohacs
    Electrophysiological experiments, Ca2+ imaging, and behavioral studies in mice identify the TRPM3 ion channel as a novel target of G-protein βγ subunits.
    1. Neuroscience

    Sleep: Shifting memories

    Hong-Viet V Ngo, Bernhard P Staresina
    A region of the brain called the putamen has a central role in memory consolidation during sleep.
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    1. Neuroscience

    Network-wide reorganization of procedural memory during NREM sleep revealed by fMRI

    Shahabeddin Vahdat, Stuart Fogel ... Julien Doyon
    Non-REM sleep is essential in the restoration of initial motor memory trace and gradual reorganization of newly-learned information underlying human procedural memory consolidation.
    1. Cell Biology
    2. Neuroscience

    The E3 ubiquitin ligase IDOL regulates synaptic ApoER2 levels and is important for plasticity and learning

    Jie Gao, Mate Marosi ... Peter Tontonoz
    Control of lipoprotein receptor protein levels at synapses by the E3 ubiquitin ligase IDOL is shown to be important for the plasticity of neuronal dendrites in vitro and learning and memory in mice.
    1. Neuroscience

    Sensory Neurons: A new target for G protein signaling

    László Csanády
    G protein-coupled receptor stimulation inhibits TRPM3 channel activity through direct binding of the Gβγ subunit to the channel.
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    1. Neuroscience

    A theory of working memory without consciousness or sustained activity

    Darinka Trübutschek, Sébastien Marti ... Stanislas Dehaene
    Visual information can be maintained in non-conscious working memory for several seconds via short-term changes in synaptic weights.
    1. Cell Biology
    2. Neuroscience

    Dual function of the PI3K-Akt-mTORC1 axis in myelination of the peripheral nervous system

    Gianluca Figlia, Camilla Norrmén ... Ueli Suter
    High PI3K-Akt-mTORC1 activity inhibits Schwann cell differentiation, while after onset of myelination, residual PI3K-Akt-mTORC1 activity promotes myelin growth.
    1. Structural Biology and Molecular Biophysics
    2. Neuroscience

    Reconciling isothermal titration calorimetry analyses of interactions between complexin and truncated SNARE complexes

    Eric A Prinslow, Chad A Brautigam, Josep Rizo
    Isothermal titration calorimetry experiments clarify apparently discrepant results described previously and show that N-terminal sequences of complexin bind to SNARE complexes containing C-terminally truncated synaptobrevin when they include the syntaxin-1 juxtamembrane region.
    1. Neuroscience

    Fast two-photon imaging of subcellular voltage dynamics in neuronal tissue with genetically encoded indicators

    Simon Chamberland, Helen H Yang ... François St-Pierre
    The combination of a new genetically encoded voltage indicator and fast two-photon imaging methods enables detection of rapid neural electrical activity in organotypic slice cultures and in living flies.
    1. Neuroscience

    Sexual dimorphism in striatal dopaminergic responses promotes monogamy in social songbirds

    Kirill Tokarev, Julia Hyland Bruno ... Henning U Voss
    Co-evolution of sexually dimorphic reinforcement systems for song can explain the coexistence of the seemingly contradictory traits of gregariousness and monogamy in social songbirds.