Browse our latest Neuroscience articles

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    1. Neuroscience

    Test of the 'glymphatic' hypothesis demonstrates diffusive and aquaporin-4-independent solute transport in rodent brain parenchyma

    Alex J Smith, Xiaoming Yao ... Alan S Verkman
    Solute movement in brain extracellular space is determined by solute diffusion, and does not depend on convection or aquaporin-4 expression as predicted by the glymphatic mechanism.
    1. Neuroscience

    Synaptic plasticity through activation of GluA3-containing AMPA-receptors

    Maria C Renner, Eva HH Albers ... Helmut W Kessels
    A novel form of hippocampal synaptic plasticity is expressed by a change in channel function of GluA3-containing AMPA-receptors.
    1. Neuroscience

    Deconstruction of the beaten Path-Sidestep interaction network provides insights into neuromuscular system development

    Hanqing Li, Ash Watson ... Kai Zinn
    A network, composed of 22 relatives of the Beaten Path and Sidestep immunoglobulin superfamily cell surface proteins, also includes several neuronal Beaten Path subfamily receptors which interact selectively with Sidestep subfamily proteins expressed on peripheral tissues.
    1. Neuroscience

    The expression of established cognitive brain states stabilizes with working memory development

    David Florentino Montez, Finnegan J Calabro, Beatriz Luna
    The excessive behavioral variability associated with adolescence is the result of greater instability of widespread or global gain signals which produces greater variability in the amplitude of expression of whole-brain states of task-related activity.
    1. Structural Biology and Molecular Biophysics
    2. Neuroscience

    Super-resolution imaging of synaptic and Extra-synaptic AMPA receptors with different-sized fluorescent probes

    Sang Hak Lee, Chaoyi Jin ... Paul R Selvin
    Small probes show that most AMPA receptors are constrained near or in the synapses.
    1. Cell Biology
    2. Neuroscience

    Modeling of axonal endoplasmic reticulum network by spastic paraplegia proteins

    Belgin Yalçın, Lu Zhao ... Cahir J O'Kane
    Proteins of the reticulon and REEP families, homologous to the products of human Hereditary Spastic Paraplegia disease genes, contribute to shaping and continuity of the axonal endoplasmic reticulum network in Drosophila.
    1. Neuroscience

    Bmal1 function in skeletal muscle regulates sleep

    J Christopher Ehlen, Allison J Brager ... Ketema N Paul
    Expression of transcription factor BMAL1 in skeletal muscle reduces the recovery response to sleep loss and is both necessary and sufficient to regulate total sleep amount.
    1. Neuroscience

    Sleep: It's not all in the brain

    Lauren J Francey, John B Hogenesch
    A clock gene expressed in skeletal muscle plays a bigger role in regulating sleep than it does in the brain.
    Version of Record
    Insight
    1. Neuroscience

    Circular oligomerization is an intrinsic property of synaptotagmin

    Jing Wang, Feng Li ... James E Rothman
    Calcium-binding synaptotagmins are involved in ring oligomer formation, which allows synaptotagmins to synchronize neurotransmitter release to Ca2+ influx.
    1. Neuroscience

    Luqin-like RYamide peptides regulate food-evoked responses in C. elegans

    Hayao Ohno, Morikatsu Yoshida ... Yuichi Iino
    Identification and functional characterization of C. elegans luqin-like arginine-tyrosine-NH2 (RYamide) peptides reveal their critical role in feeding-related processes.