Browse our latest Neuroscience articles

Syntaxin 4 regulates retrograde signaling in the postsynaptic compartment at Drosophila synapses by controlling trafficking of Neuroligin and Synaptotagmin 4 cargo.

Peptidergic neurons regulate undulation and turning movements to enable Caenorhabditis elegans to gradually adjust its locomotion strategy from dispersal to local search.

Male and female mice differ in basal cerebellar physiology, including the magnitude of synaptic excitation by metabotropic glutamate receptors, kinetics of synaptic inhibition, intrinsic properties, and responses to autism-linked mutations.

When the Ca²⁺-binding loops of the C2B domain insert into a membrane, interactions with a phospholipid and the SNARE complex allow synaptotagmin-1 to bend the membrane.

Extrasynaptic GABA_A receptors that emerge at puberty trigger adolescent synaptic pruning; pruning is prevented and cognition is impaired if the receptors are absent.

The enzyme PKMzeta is crucial for the maintenance of long-term memories, but a closely related enzyme provides a back-up should PKMzeta fail, thus explaining the controversy over why deleting the gene for PKMzeta may not appear to impair memory.

Ca_V1.3 channels of the short isoform are coupled via their C-terminal domains in a Ca²⁺-CaM-dependent manner, which facilitates Ca²⁺ influx and increases the discharge of hippocampal neurons.

Gut microbiota can influence mPFC transcriptional profiles and myelin content, overriding the impact of genetic background in the development of social avoidance behavior.