Michael JD Daniels, Lucas Lefevre ... Barry W McColl
Cst7, a gene coding for protein cystatin F, is expressed by microglia in neurodegenerative disease models and mediates sex-dependent effects on microglial endolysosomal function and disease pathology.
Melanopsin phototransduction targets distinct complements of transduction channels across intrinsically photosensitive retinal ganglion cell subtypes and does not require hyperpolarization-activated cyclic nucleotide-gated channels.
The hippocampus demonstrates flexible coding during memory encoding, prioritizing either distance or time information based on the specific requirements of the experiment.
A neural network model of the hippocampus exhibits a division of labor across its two main pathways during category learning, with one pathway specializing in extracting systematic category information and another in encoding arbitrary details.
Hirofumi Noguchi, Jessica Chelsea Arela ... Samuel Pleasure
Hilar mossy cells control seizure-dependent dentate neurogenesis and stem cell quiescence by activity-dependent control of Sonic hedgehog production and signaling.
When the acquisition of reward becomes effortful, marmosets choose to work longer, delaying their harvest, but slow their movements, reducing energy consumption.
Anterior Cingulate Cortex displays robust tracking during strategy execution of a summary statistic for that strategy in recent behavioral history, suggesting a role for this brain region in estimating which actions promote the occurrence of events in the environment.