Browse our latest Physics of Living Systems articles

Single-molecule tracking at scale, analyzing millions of cells and thousands of compounds per day, demonstrates that measuring protein motion provides mechanistic insights relevant to drug discovery.

The composition of nodes that effectively transmit sinusoidal waves in a model network resembling C. elegans' electrical synapses network changes according to the waves' wavenumber.

Fish swimming in groups can either conserve or expend energy during collective movement, depending on their spatial position within the school.

Active and passive contributions to cell shape change and rearrangements can be distinguished from observed cell geometry, revealing the self-organization mechanisms underlying internally-driven epithelial convergent extension.

The viscous hydraulics of contracting endoplasmic reticulum networks challenge common solute transport theories, suggesting the contraction of peripheral sheets as a plausible driving mechanism.

Poor intracellular availability and diffusion of weakly basic, small molecule drugs can be greatly enhanced by preventing ion trapping in crowded cellular environments.

A minimal mathematical model can explain the emergence of planar cell polarity in epithelial tissues using only three free parameters, namely the rate of protein binding to cell membrane, the intracellular protein concentration, and the steepness of tissue-level gradients.