Browse our latest Physics of Living Systems articles

Action potentials of neurons expel a charge when they reach the axon terminal, and classical electrodynamics predict the resulting electric fields and its influence to other neurons by ephaptic coupling.

Computational modelling suggests that the segmentation clock and the morphogenesis of the pre-somitic mesoderm exhibit developmental modularity, enabling the independent evolution of these processes and possibly contributing to the high evolvability of vertebrate segment number.

Electrical signaling is demonstrated in Escherichia coli biofilms.

A differentiable variant of the Gillespie algorithm enables gradient-based optimization for stochastic chemical kinetics, facilitating efficient parameter estimation and the design of biochemical networks with desired input–output relationships.

Mathematical models of horizontal gene transfer reveal the determinants underlying multistability of microbial communities, offering key insights for the predictive control and engineering of complex microbiota.

A catalytic growth model in a shared enzyme pool explains robust centrosome size equality and size scaling, offering a unifying model for centrosome maturation dynamics across diverse organisms.

A computational systems biology approach identifies a gene network module associated with single-cell mechanical phenotype changes across diverse mouse and human systems, with implications for on-demand engineering of cell stiffness.

Phase diagrams for 140 variants of prion-like low-complexity domains are computed to establish scaling laws that quantify the impact of amino acid mutations on the thermodynamic stability of condensates.