Browse our latest Physics of Living Systems articles

Page 11 of 54
    1. Neuroscience
    2. Physics of Living Systems

    Neural criticality from effective latent variables

    Mia C Morrell, Ilya Nemenman, Audrey Sederberg
    Signatures of criticality that have been observed across diverse neural systems, such as power-law avalanche distributions and exponent relationships, can arise without fine-tuning in networks coupled to latent, dynamical variables.
    1. Physics of Living Systems

    A unified approach to dissecting biphasic responses in cell signaling

    Vaidhiswaran Ramesh, J Krishnan
    In-built competing effects are present at different levels in signaling networks, starting from basic biochemical building blocks to the network level, and mathematical and computational analysis reveals when they give rise to biphasic responses and what the consequences are.
    1. Cell Biology
    2. Physics of Living Systems

    The positioning mechanics of microtubule asters in Drosophila embryo explants

    Jorge de-Carvalho, Sham Tlili ... Ivo A Telley
    Using cytosolic explants from Drosophila syncytial embryos combined with quantitative microscopy and perturbations, the mechanical forces separating Drosophila microtubule asters are revealed.
    1. Microbiology and Infectious Disease
    2. Physics of Living Systems

    Energetics of the microsporidian polar tube invasion machinery

    Ray Chang, Ari Davydov ... Manu Prakash
    Unraveling the ultrafast polar tube ejection in microsporidia reveals extreme cellular hydraulics, providing a data-driven model for infectious cargo transport, with implications for physical approaches to understanding microsporidia transmission.
    1. Physics of Living Systems

    Diameter dependence of transport through nuclear pore complex mimics studied using optical nanopores

    Nils Klughammer, Anders Barth ... Cees Dekker
    Nuclear pore complex mimics based on solid-state nanopores show significant selectivity below a diameter of 55 nm, which decreases gradually for larger pore diameters.
    1. Physics of Living Systems

    Energy conservation by collective movement in schooling fish

    Yangfan Zhang, George V Lauder
    Fish schools showed an U-shaped metabolism-speed curve and reduced the energy use per tail beat up to 56% at high swimming speeds compared to solitary fish.
    1. Computational and Systems Biology
    2. Physics of Living Systems

    How microscopic epistasis and clonal interference shape the fitness trajectory in a spin glass model of microbial long-term evolution

    Nicholas M Boffi, Yipei Guo ... Ariel Amir
    High-resolution simulations of evolving microbial populations reveal that microscopic epistasis slows the rate of adaptation, while clonal interference can either speed it up or leave it fixed.
    1. Developmental Biology
    2. Physics of Living Systems

    Core PCP mutations affect short-time mechanical properties but not tissue morphogenesis in the Drosophila pupal wing

    Romina Piscitello-Gómez, Franz S Gruber ... Suzanne Eaton
    Quantitative analysis of cell dynamics over a range of timescales reveals that core PCP is not required to organize large-scale tissue flows but does affect short timescale mechanics.
    1. Physics of Living Systems

    The ability to sense the environment is heterogeneously distributed in cell populations

    Andrew Goetz, Hoda Akl, Purushottam Dixit
    Information transduction capacity of mammalian cells is high and varies substantially from cell to cell.
    1. Cell Biology
    2. Physics of Living Systems

    Protein Tracking: Everything, everywhere, almost at once

    Jacob Kæstel-Hansen, Nikos S Hatzakis
    A new platform that can follow the movement of individual proteins inside millions of cells in a single day will help contribute to existing knowledge of cell biology and identify new therapeutics.
    Version of Record
    Insight