Browse our latest Physics of Living Systems articles

Relative hydraulic resistance, shear rate, and pressure in a vascular network integrate the network's architecture via fluid flow, and determine vein dynamics, with a time delay, in the prototypical organism Physarum polycephalum.

A combination of in toto imaging and theory suggests a new mechanism for the remodeling of veins in vascular networks.

Muscle synergies are able to identify muscular adaptation that results from feelings of joint instability, whereas tibiofemoral kinematics are sensitive for detecting acute instability events during functional activities.

Directed mechanical stresses can trigger active T1 events that lead to tissue elongation perpendicular to the main direction of tissue stress.

Thermodynamic, kinetic, and dynamic analyses as well as solubility proteome profiling reveal that influenza A virus liquid inclusions may be selectively hardened with promising antiviral activity.

Understanding how to harden liquid condensates produced by influenza A virus could accelerate the development of novel antiviral drugs.

Bacterial CRISPR immunity tracks phage mutations, creating immune diversity in bacterial populations that parallels phage genetic diversity and patterns of phage evolution that are determined by the type and degree of immune cross-reactivity in the CRISPR system.

The observed activity of the motor cortex in space and time is reproduced by a model with a specific structure of the inputs to the motor cortex.

Using self-organization, cells can collectively leverage defects in nematic and hexatic orders to localize mechanical stresses and remove an unwanted cell with their preferred path to achieve this explored here by independently tuning cell–cell and cell–substrate adhesion strengths.

Microbial cells optimally structure their proteomes in order to mutually maximize metabolism and translation, as established by an extensive comparison between data and a low-dimensional model of cellular physiology.