Browse our latest Stem Cells and Regenerative Medicine articles

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    1. Neuroscience
    2. Stem Cells and Regenerative Medicine

    Promoting axon regeneration by inhibiting RNA N6-methyladenosine demethylase ALKBH5

    Dong Wang, Tiemei Zheng ... Bin Yu
    Inhibiting RNA N6-methyladenosine demethylase ALKBH5 promoted axonal regeneration of dorsal root ganglion neurons by regulating stability of Lpin2 mRNA and enhanced the survival and axonal regeneration of retinal ganglion cells.
    1. Neuroscience
    2. Stem Cells and Regenerative Medicine

    Rubella virus tropism and single-cell responses in human primary tissue and microglia-containing organoids

    Galina Popova, Hanna Retallack ... Tomasz Nowakowski
    Combination of primary brain culture and single-cell RNA sequencing in brain organoids identifies microglia as the main target of rubella virus infection.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Combined lineage tracing and scRNA-seq reveals unexpected first heart field predominance of human iPSC differentiation

    Francisco X Galdos, Carissa Lee ... Sean M Wu
    TBX5 lineage tracing and high resolution single cell transcriptomics uncover the predominance of first heart field development during human-induced pluripotent stem cell cardiac differentiation.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Cardiac Development: Tracing the history of a heart

    Brian Spurlock, Li Qian
    Newly developed tools will help researchers understand how the human heart develops and build better models to study and treat congenital heart disease.
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    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Low-level repressive histone marks fine-tune gene transcription in neural stem cells

    Arjun Rajan, Lucas Anhezini ... Cheng-Yu Lee
    Stem-cell-specific transcriptional repressors fine-tune levels of stemness gene transcripts in asymmetrically dividing neural stem cells by depositing low levels of repressive histone marks at these loci allowing progeny to rapidly initiate differentiation.