Browse our latest Stem Cells and Regenerative Medicine articles

Stem-cell-based neural replacement, in combination with optogenetic stimulation, could represent a translationally viable therapeutic strategy to overcome atrophy and paralysis of targeted muscles in people living with amyotrophic lateral sclerosis.

Activation of Activin A-expressing progenitor cells emerges as a pivotal mechanism in bone fracture healing, shedding light on a potential therapeutic avenue to augment bone repair processes.

Analysis of the osteochondral unit of aquatic mammals reveals a distinctly different tissue structure, lacking the arcade-like collagen fiber organization, a calcified cartilage layer and a dense subchondral bone plate, typically seen in osteochondral tissue of terrestrial mammals.

A novel strategy to activate the WNT pathway in a cell type selective manner by linking designer ligands with target cell specific bridging receptors.

The signaling requirements to decouple proliferation of pancreatic progenitors from differentiation were elucidated and employed for the reproducible expansion, under GMP-compliant conditions, of pancreatic progenitors derived from different human pluripotent stem cell lines.

Dysregulated erythroblast-specific iron trafficking and regulation of iron metabolism provides evidence of a novel potential therapeutic target to reverse ineffective erythropoiesis in MDS.

Exposure of embryonic stem cells to physiological concentrations of Δ9-THC remodels cellular metabolism across differentiation.

The psychoactive component of cannabis, ∆9-THC, affects cell growth and metabolism in early embryonic cell types in mice.