Browse our latest Stem Cells and Regenerative Medicine articles

A genetic tracing study demonstrates that neural progenitor lineage dominance may not be maintained in differentiated progeny, underscoring the critical need for region-specific markers to validate pluripotent stem cell–derived products.

Extending hypoxia signalling after birth extends the window of heart regeneration.

The development of novel separation-of-function mutants has uncovered non-canonical chromatin roles of IκBα in regulating mouse embryonic stem cell pluripotency and differentiation, independently of the classical NF-κB pathway.

Bioluminescence imaging in live mice was used to assess the abilities of systemically introduced adeno-associated viral capsids containing enhancer regulatory sequences to target transgene expression to myocardial injuries.

Inhibition of the endothelin B receptor (ETBR) with FDA-approved Bosentan enhances axon regeneration and reverses age-related decline, revealing a promising therapeutic target for improving nerve repair in older individuals.

Self-renewal heterogeneity causes myeloid skewing.

Stochastic intrinsic fate decisions by planarian stem cells drive clonal expansion and reveal a straightforward, feedback‐independent mechanism for robust cell identity selection.

PRDM16 directs BMP signaling outcomes by guiding SMAD complex genomic binding to repress neural stem cell proliferation and promote choroid plexus epithelial specification.