Browse our latest Stem Cells and Regenerative Medicine articles

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    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Regulation of multiple signaling pathways promotes the consistent expansion of human pancreatic progenitors in defined conditions

    Luka Jarc, Manuj Bandral ... Anthony Gavalas
    The signaling requirements to decouple proliferation of pancreatic progenitors from differentiation were elucidated and employed for the reproducible expansion, under GMP-compliant conditions, of pancreatic progenitors derived from different human pluripotent stem cell lines.
    1. Medicine
    2. Stem Cells and Regenerative Medicine

    Iron chelation improves ineffective erythropoiesis and iron overload in myelodysplastic syndrome mice

    Wenbin An, Maria Feola ... Yelena Ginzburg
    Dysregulated erythroblast-specific iron trafficking and regulation of iron metabolism provides evidence of a novel potential therapeutic target to reverse ineffective erythropoiesis in MDS.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Metabolic memory of Δ9-tetrahydrocannabinol exposure in pluripotent stem cells and primordial germ cells-like cells

    Roxane Verdikt, Abigail A Armstrong ... Patrick Allard
    Exposure of embryonic stem cells to physiological concentrations of Δ9-THC remodels cellular metabolism across differentiation.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Stem Cells: Investigating the impact of cannabis

    Merrick Pierson Smela
    The psychoactive component of cannabis, ∆9-THC, affects cell growth and metabolism in early embryonic cell types in mice.
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    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    The reciprocal regulation between mitochondrial-associated membranes and Notch signaling in skeletal muscle atrophy

    Yurika Ito, Mari Yamagata ... Takahiko Sato
    The maintenance of proper mitochondrial-associated endoplasmic reticulum membranes is crucial for preventing skeletal muscle atrophy to interact with the Notch signaling pathway.