Browse our latest Stem Cells and Regenerative Medicine articles

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    1. Stem Cells and Regenerative Medicine

    Regeneration following tissue necrosis is mediated by non-apoptotic caspase activity

    Jacob W Klemm, Chloe Van Hazel, Robin E Harris
    A non-apoptotic function of the caspase Dronc is essential to promote tissue repair in response to necrosis via a previously uncharacterized mechanism.
    1. Stem Cells and Regenerative Medicine

    Autologous P63+ lung progenitor cell transplantation in idiopathic pulmonary fibrosis: a phase 1 clinical trial

    Shiyu Zhang, Min Zhou ... Wei Zuo
    It is safe to transplant autologous P63+ progenitor cells isolated from healthy bronchi to IPF patients for the treatment of IPF, and preliminary efficacy has been demonstrated in some patients.
    1. Stem Cells and Regenerative Medicine

    Proteome dynamics reveal Leiomodin 1 as a key regulator of myogenic differentiation

    Ellen Späth, Svenja C Schüler ... Alessandro Ori
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Stem Cells and Regenerative Medicine

    Clonal analysis of murine HSC self-renewal and differentiation in native hematopoiesis

    Chenyu You, Zhen Zhang ... Jianlong Sun
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Neuroscience
    2. Stem Cells and Regenerative Medicine

    Axon-specific microtubule regulation drives asymmetric regeneration of sensory neuron axons

    Ana Catarina Costa, Blanca R Murillo ... Monica M Sousa
    Proteomic analyses reveal a distinct protein signature underlying microtubule organization and regenerative asymmetries in sensory neuron axons, supported by an in vitro system replicating key features of sensory neuron biology.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Stochastic cell-intrinsic stem cell decisions control colony growth in planarians

    Tamar Frankovits, Prakash Varkey Cherian ... Omri Wurtzel
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    SMARCAD1 and TOPBP1 contribute to heterochromatin maintenance at the transition from the 2C-like to the pluripotent state

    Ruben Sebastian-Perez, Shoma Nakagawa ... Maria Pia Cosma
    The chromatin-bound proteome of embryonic stem cells transitioning to 2C-like cells uncovers chromatin regulators involved in heterochromatin formation.
    1. Stem Cells and Regenerative Medicine

    Identification of a sub-population of synovial mesenchymal stem cells with enhanced treatment efficacy in a rat model of Osteoarthritis

    Nedaa Al-Jezani, Asmaa Affan ... Roman J Krawetz
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Medicine
    2. Stem Cells and Regenerative Medicine

    R-Spondin Mimetic, SZN-043, Induced Proliferation and Wnt Activity, Two Features Deficient in Human Alcohol-Associated Liver Disease

    Trevor Fisher, Mehaben Patel ... Helene Baribault
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    • Incomplete
    1. Stem Cells and Regenerative Medicine

    Il-6 signaling exacerbates hallmarks of chronic tendon disease by stimulating reparative fibroblasts

    Tino Stauber, Greta Moschini ... Jess G Snedeker
    IL-6 signaling drives fibroblast activation in tendinopathy, emerging as a promising therapeutic target for these increasingly prevalent and costly tendon conditions.