Browse our latest Stem Cells and Regenerative Medicine articles

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    1. Neuroscience
    2. Stem Cells and Regenerative Medicine

    Directed differentiation of functional corticospinal-like neurons from endogenous SOX6+/NG2+ cortical progenitors

    Abdulkadir Ozkan, Hari K Padmanabhan ... Jeffrey D Macklis
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Compelling
    1. Stem Cells and Regenerative Medicine

    Epigenetic insights into GABAergic development in Dravet Syndrome iPSC and therapeutic implications

    Jens Schuster, Xi Lu ... Xingqi Chen
    Analyses of epigenetic profiles using ATAC-seq provide a comprehensive investigation of the chromatin landscape in hampered GABAergic differentiation in a DS-patient iPSC-derived disease model.
    1. Neuroscience
    2. Stem Cells and Regenerative Medicine

    Endothelin B receptor inhibition rescues aging-dependent neuronal regenerative decline

    Rui Feng, Sarah F Rosen ... Valeria Cavalli
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Neuroscience
    2. Stem Cells and Regenerative Medicine

    Circulating platelets modulate oligodendrocyte progenitor cell differentiation during remyelination

    Amber R Philp, Carolina R Reyes ... Francisco J Rivera
    Transient platelet accumulation supports oligodendrocyte progenitor cell differentiation during myelin repair, while sustained exposure to elevated platelet numbers hampers the generation of remyelinating cells.
    Version of Record
    Short Report
    • Important
    • Convincing
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Temporally resolved early bone morphogenetic protein-driven transcriptional cascade during human amnion specification

    Nikola Sekulovski, Jenna C Wettstein ... Kenichiro Taniguchi
    Analyses of transcriptomic dynamics in a new model of human amnion formation identify five continuous amniogenic transcriptional phases as well as a critical role of TFAP2A in amnion fate progression.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Direct lineage conversion of postnatal mouse cortical astrocytes to oligodendrocyte lineage cells

    Justine Bajohr, Erica Y Scott ... Maryam Faiz
    Not revised
    Reviewed Preprint v1
    • Useful
    • Solid
    1. Stem Cells and Regenerative Medicine

    Defining mononuclear phagocyte distribution and behaviour in the zebrafish heart

    Bethany Moyse, Joanna Moss ... Rebecca J Richardson
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Neuroscience
    2. Stem Cells and Regenerative Medicine

    Human adherent cortical organoids in a multiwell format

    Mark van der Kroeg, Sakshi Bansal ... Femke MS de Vrij
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Stem Cells and Regenerative Medicine

    Hematopoiesis: Counting blood precursors

    Sarah Duchamp de Chastaigne, Catherine M Sawai
    A new mathematical model can estimate the number of precursor cells that contribute to regenerating blood cells in mice.
    Version of Record
    Insight
    1. Cell Biology
    2. Stem Cells and Regenerative Medicine

    Differential regulation by CD47 and thrombospondin-1 of extramedullary erythropoiesis in mouse spleen

    Rajdeep Banerjee, Thomas J Meyer ... David D Roberts
    Increased extramedullary erythropoiesis in spleen compensates for the elevated turnover of red blood cells in mice lacking CD47, but extramedullary erythropoiesis is suppressed in mice lacking the CD47 ligand thrombospondin-1.
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