Browse our latest Stem Cells and Regenerative Medicine articles

Page 8 of 55
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Negative cell cycle regulation by calcineurin is necessary for proper beta cell regeneration in zebrafish

    Laura Massoz, David Bergemann ... Isabelle Manfroid
    Calcineurin fine tunes the balance between proliferation and differentiation of Notch-responsive progenitors in the pancreatic ducts to enable beta cell regeneration in zebrafish.
    1. Neuroscience
    2. Stem Cells and Regenerative Medicine

    Muscle-resident mesenchymal progenitors sense and repair peripheral nerve injury via the GDNF-BDNF axis

    Kyusang Yoo, Young-Woo Jo ... Young-Yun Kong
    GDNF receptor-expressing mesenchymal progenitor subpopulation within skeletal muscle responds to peripheral nerve injury by sensing GDNF and secreting BDNF, thereby directly promoting nerve regeneration through facilitating remyelination by Schwann cells.
    1. Neuroscience
    2. Stem Cells and Regenerative Medicine

    Reprogramming: A perfect recipe for a corticospinal neuron

    Alfonso Aguilera, Marta Nieto
    A tailored cocktail of genes can reprogram a subset of progenitors to no longer produce glial cells and instead develop into neurons involved in motor control.
    Version of Record
    Insight
    1. Stem Cells and Regenerative Medicine

    Glial ferritin maintains neural stem cells via transporting iron required for self-renewal in Drosophila

    Zhixin Ma, Wenshu Wang ... Su Wang
    Iron content in neural stem cells controlled by glial ferritin is critical for self-renewal and proliferation of neural stem cells.
    1. Stem Cells and Regenerative Medicine

    Sox9 marks limbal stem cells and is required for asymmetric cell fate switch in the corneal epithelium

    Gabriella Rice, Olivia Farrelly ... Panteleimon Rompolas
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Compelling
    1. Stem Cells and Regenerative Medicine

    Epigenetic insights into GABAergic development in Dravet Syndrome iPSC and therapeutic implications

    Jens Schuster, Xi Lu ... Xingqi Chen
    Analyses of epigenetic profiles using ATAC-seq provide a comprehensive investigation of the chromatin landscape in hampered GABAergic differentiation in a DS-patient iPSC-derived disease model.
    1. Neuroscience
    2. Stem Cells and Regenerative Medicine

    Circulating platelets modulate oligodendrocyte progenitor cell differentiation during remyelination

    Amber R Philp, Carolina R Reyes ... Francisco J Rivera
    Transient platelet accumulation supports oligodendrocyte progenitor cell differentiation during myelin repair, while sustained exposure to elevated platelet numbers hampers the generation of remyelinating cells.
    Version of Record
    Short Report
    • Important
    • Convincing
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Temporally resolved early bone morphogenetic protein-driven transcriptional cascade during human amnion specification

    Nikola Sekulovski, Jenna C Wettstein ... Kenichiro Taniguchi
    Analyses of transcriptomic dynamics in a new model of human amnion formation identify five continuous amniogenic transcriptional phases as well as a critical role of TFAP2A in amnion fate progression.
    1. Stem Cells and Regenerative Medicine

    Defining mononuclear phagocyte distribution and behaviour in the zebrafish heart

    Bethany Moyse, Joanna Moss ... Rebecca J Richardson
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Stem Cells and Regenerative Medicine

    Hematopoiesis: Counting blood precursors

    Sarah Duchamp de Chastaigne, Catherine M Sawai
    A new mathematical model can estimate the number of precursor cells that contribute to regenerating blood cells in mice.
    Version of Record
    Insight