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    1. Medicine
    2. Neuroscience

    Juvenile reinstatement of TCF4 in Pitt-Hopkins syndrome model mice reveals a critical window for genetic intervention

    Lucas M James, Carlee A Friar ... Benjamin D Philpot
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Medicine
    2. Immunology and Inflammation

    A translational transcriptomic signature of vaccine reactogenicity for the evaluation of novel formulations

    Jérémie Becker, Maroussia Roelens ... Laurent Beloeil
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Neuroscience

    PSD-95 drives binocular vision maturation critical for predation

    Subhodeep Bhattacharya, Livia JF Wilod Versprille ... Siegrid Löwel
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    • Inadequate
    1. Biochemistry and Chemical Biology

    Cul5Wsb2 uses BCL2 proteins as co-receptors to target Bim for degradation

    Wilhelm Vaysse-Zinkhöfer, Enya Marie Catherine Alcindor ... David Paul Toczyski
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Cell Biology

    Abnormal shear stress induces ferroptosis in endothelial cells via KLF6 downregulation

    Jingang Cui, Zhiyu Fan ... Yongsheng Ding
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Compelling
    1. Computational and Systems Biology
    2. Neuroscience

    Motor biases reflect a misalignment between visual and proprioceptive reference frames

    Tianhe Wang, J Ryan Morehead ... Jonathan S Tsay
    The pattern of reaching biases is stable across contexts and can be attributed to a misalignment between eye-centric and body-centric representations of position.
    1. Neuroscience

    Temporal dynamics of peri-microsaccadic modulations within the foveola

    Zoe Stearns, Martina Poletti
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Computational and Systems Biology

    Ribosome demand links transcriptional bursts to protein expression noise

    Sampriti Pal, Upasana Ray, Riddhiman Dhar
    Propagation of expression noise from mRNA to protein level is influenced by variation in availability of ribosomal machinery.
    1. Developmental Biology
    2. Neuroscience

    Cell cycle-dependent cues regulate temporal patterning of the Drosophila central brain neural stem cells

    Gonzalo N Morales Chaya, Mubarak Hussain Syed
    Intrinsic cell cycle progression governs developmental time in neural stem cells by regulating temporal gene transitions that generate neural diversity.
    1. Cell Biology
    2. Immunology and Inflammation

    Male-biased Cyp17a2 orchestrates antiviral sexual dimorphism in fish via STING stabilization and viral protein degradation

    Long-Feng Lu, Bao-jie Cui ... Shun Li
    Cyp17a2 enhances antiviral responses in male zebrafish by stabilizing STING through TRIM11-mediated K33-linked polyubiquitination, boosting IFN production.
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