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    1. Neuroscience

    Multiple and subject-specific roles of uncertainty in reward-guided decision-making

    Alexander Paunov, Maëva L’Hôtellier ... Florent Meyniel
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Neuroscience
    2. Computational and Systems Biology

    Neural dynamics of reversal learning in the prefrontal cortex and recurrent neural networks

    Christopher M Kim, Carson C Chow, Bruno B Averbeck
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Neuroscience

    Inverted encoding of neural responses to audiovisual stimuli reveals super-additive multisensory enhancement

    Zak Buhmann, Amanda K Robinson ... Reuben Rideaux
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Neuroscience

    Mid1 deletion leads to cognitive dysfunction in Opitz syndrome by regulates neural rhythms through the inhibition of p-Creb by PP2Ac

    Ziye Yang, Pengxiang Li ... Dong Ming
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Neuroscience

    It’s the Sound, not the Pulse: Peripheral Magnetic Stimulation Reduces Central Sensitization through Auditory Modulatory Effects

    Spencer S Abssy, Natalie R Osborne ... Massieh Moayedi
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Developmental Biology
    2. Genetics and Genomics

    Rescuable sleep and synaptogenesis phenotypes in a Drosophila model of O-GlcNAc transferase intellectual disability

    Ignacy Czajewski, Bijayalaxmi Swain ... Daan MF van Aalten
    Modelling O-GlcNAc transferase intellectual disability reveals the roles of this post-translational modification in regulating normal axonal terminal morphology and maintaining appropriate sleep homeostasis, pharmacological and genetic rescues of O-GlcNAcylation highlight the complexities of addressing this disorder.
    1. Developmental Biology
    2. Neuroscience

    Lineage-specific intersection of endothelin and GDNF signaling in enteric nervous system development

    Denise M Poltavski, Alexander T Cunha ... Takako Makita
    Neural crest and placode lineages both contribute to the enteric nervous system, divergently utilizing Edn3-Ednrb and GDNF-Ret signaling.
    1. Stem Cells and Regenerative Medicine

    Single-nucleus transcriptomics reveal the differentiation trajectories of periosteal skeletal/stem progenitor cells in bone regeneration

    Simon Perrin, Maria Ethel ... Céline Colnot
    A single-nucleus atlas of bone repair uncovers the trajectories of periosteal skeletal stem/progenitor cells in response to fracture and identifies injury-induced fibrogenic cells as intermediate osteochondroprogenitors and key paracrine regulators.
    1. Developmental Biology

    Maternal obesity may disrupt offspring metabolism by inducing oocyte genome hyper-methylation via increased DNMTs

    Shuo Chao, Jun Lu ... Zhao-Jia Ge
    Maternal obesity mouse model reveal that melatonin deficiency causes the genomic hyper-methylation of oocytes via increasing the expression of DNA methyltransferases.
    1. Cancer Biology

    Increased inflammatory signature in myeloid cells of non-small cell lung cancer patients with high clonal hematopoiesis burden

    Hyungtai Sim, Hyun Jung Park ... Murim Choi
    In metastatic NSCLC patients, CHIP showed minimal impact on immunotherapy response but was more prevalent and associated with inflammatory pathways in myeloid cells, particularly in lung squamous cell carcinoma.
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