In astrocytes, there exists an intrinsic spatial threshold of subcellular calcium levels that triggers an astrocyte calcium surge throughout the cell, demonstrating cellular astrocyte calcium integration of time and space.
Maryam Rahimi-Balaei, Shayan Amiri ... Hassan Marzban
A distinct subset of cerebellar nuclei neurons originates from a previously unrecognized germinal zone within the cerebellar primordium, independent of Atoh1 influence, highlighting new cellular origins in cerebellar development.
The important role of structural asymmetry in the functional lateralization of the same brain area provides a crucial insight into the neurobiological fundament for human brain's functional lateralization.
Felix Lankester, Tito J Kibona ... Sarah Cleaveland
Livestock abortion surveillance can capture valuable information on important livestock pathogens, including those that are zoonotic and with epidemic potential, revealing importance of timely collection of diagnostic samples for attribution.
Co-release of the functionally opposing fast neurotransmitters, glutamate and GABA, from distinct synaptic vesicles within the same supramammillary synaptic terminal modulates dentate granule cell firing in a frequency-dependent manner.
Attentional modulation is affected by target-distractor similarity, indicating tuning sharpening as the underlying mechanism for response enhancement during object-based attention.
Quan-Son Eric Le, Daniel Hereford ... Jonathan P Fadok
Associative and non-associative learning mechanisms summate to produce robust and complex conditioned behavior profiles, opening new avenues to in-depth investigations of defensive responses and threat evaluation.
TIM23 core deficiency specifically impacts the oxidative phosphorylation and the mitochondrial ribosome complexes and, unexpectedly, leads to reduction of plasma membrane voltage-dependent potassium channels in neurons.
An accurate and efficient biologically plausible statistical model of the spiking activity of neural populations shows computational benefits of homeostatic synaptic scaling in learning large neural population codes.
Gerbils exhibit stable, family-specific vocal dialects over weeks, suggesting vocal communication may play a key role in representing kinship in natural social groups.
