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The naturally occurring biologics, FLO and HC-HA/PTX3, derived from human birth tissues, may be developed as a much-needed non-opioid therapy for post-surgical pain treatment, leveraging robust neuronal mechanisms.

T cells, neutrophils, and protista Dictyostelium undergo amoeboid durotaxis which involves soft end polarized NMIIA.

The speed of intraflagellar transport, influenced by particle size, shows a positive correlation with ciliary length in zebrafish.

CCDC113 is a key structural hub for sperm axoneme and head-tail coupling apparatus (HTCA) stability, with defects leading to male infertility through disruption of sperm flagellar and HTCA integrity.

Kiss1^ARH neurons transition from synchronous to burst firing under preovulatory levels of E2, causing a shift from peptidergic to glutamatergic transmission that drives the GnRH surge through enhanced glutamate neurotransmission.

A noisy cell-intrinsic timer provides positional information for the segmentation clock, modulated by extrinsic factors such as FGF.

The viscous hydraulics of contracting endoplasmic reticulum networks challenge common solute transport theories, suggesting the contraction of peripheral sheets as a plausible driving mechanism.

Studies with mice and brain organoids models reveals that dysregulation of GTF2IRD1-TTR-ERK pathway significantly contributes to neuronal deficits of Williams syndrome.

During Drosophila primordial germ cells (PGCs) specification, the centrosome and germplasm are subject to regulation, during the maternal zygotic transition, by Caspar/TER94-dependent degradative pathways that influence PGC determinants.

Ablation of olfactory projection neurons in adult mice triggers sprouting of the apical dendrite of remaining neurons towards multiple nearby glomeruli and disrupts the odor map.