Browse our latest research

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    1. Neuroscience

    Value construction through sequential sampling explains serial dependencies in decision making

    Ariel Zylberberg, Akram Bakkour ... Michael N Shadlen
    The subjective value of choice options changes during deliberation, and accounting for these changes improves predictions of choices, response times, and BOLD fMRI activity.
    1. Neuroscience

    A novel image segmentation method based on spatial autocorrelation identifies A-type potassium channel clusters in the thalamus

    Csaba Dávid, Kristóf Giber ... Laszlo Acsady
    The spatial autocorrelation method Local Moran’s I was used for image segmentation to delineate pixel clusters representing congruous objects with fuzzy borders, in this case potassium ion channel clusters.
    1. Computational and Systems Biology
    2. Evolutionary Biology

    Quantifying microbial fitness in high-throughput experiments

    Justus Wilhelm Fink, Michael Manhart
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Structural Biology and Molecular Biophysics

    Protonation/deprotonation-driven switch for the redox stability of low-potential [4Fe-4S] ferredoxin

    Kei Wada, Kenji Kobayashi ... Masaki Unno
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Compelling
    1. Neuroscience

    Efficient value synthesis in the orbitofrontal cortex explains how loss aversion adapts to the ranges of gain and loss prospects

    Jules Brochard, Jean Daunizeau
    Computational modeling shows how neural mechanisms for mitigating biological constraints (such as neurons’ limited firing range) may eventually result in complex though predictable irrational behavior.
    1. Computational and Systems Biology
    2. Neuroscience

    Decoding contextual influences on auditory perception from primary auditory cortex

    Bernhard Englitz, Sahar Akram ... Shihab Shamma
    The perception of ambiguous steps in relative tone height is predicted by direction-selective cells in the auditory cortex, rather than the brain's represented distance between the tone heights.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Endogenous oligomer formation underlies DVL2 condensates and promotes Wnt/β-catenin signaling

    Senem Ntourmas, Martin Sachs ... Dominic B Bernkopf
    Biochemical detection of endogenous, paralog-specific DVL2 complexes, molecular characterization of underlying protein domains and functional evidence for their importance extend the knowledge of Wnt pathway regulation through DVL2 biomolecular condensates.
    1. Ecology

    Polarised moonlight guides nocturnal bull ants home

    Cody A Freas, Ajay Narenda ... Ken Cheng
    Large eyed bull ants are able to use the exceedingly dim lunar polarised light pattern in the overhead sky to navigate back to the nest at night.
    1. Neuroscience

    The identification of extensive samples of motor units in human muscles reveals diverse effects of neuromodulatory inputs on the rate coding

    Simon Avrillon, François Hug ... Dario Farina
    Motor units within a pool exhibit distinct rate coding as force levels change, highlighting how gain control can transform inputs with limited bandwidth into the desired muscle force.
    1. Stem Cells and Regenerative Medicine

    Pharmacologically inducing regenerative cardiac cells by small molecule drugs

    Wei Zhou, Kezhang He ... Sheng Ding
    Induction of regenerative cardiac cells (RCCs) from human embryonic stem cell-derived cardiomyocytes and neonatal rat cardiomyocytes using a novel two-compound treatment enhances heart function following myocardial infarction and offers a promising avenue for cardiac regeneration through transcriptional and epigenetic reprogramming.