Ariel Zylberberg, Akram Bakkour ... Michael N Shadlen
The subjective value of choice options changes during deliberation, and accounting for these changes improves predictions of choices, response times, and BOLD fMRI activity.
The spatial autocorrelation method Local Moran’s I was used for image segmentation to delineate pixel clusters representing congruous objects with fuzzy borders, in this case potassium ion channel clusters.
Computational modeling shows how neural mechanisms for mitigating biological constraints (such as neurons’ limited firing range) may eventually result in complex though predictable irrational behavior.
The perception of ambiguous steps in relative tone height is predicted by direction-selective cells in the auditory cortex, rather than the brain's represented distance between the tone heights.
Senem Ntourmas, Martin Sachs ... Dominic B Bernkopf
Biochemical detection of endogenous, paralog-specific DVL2 complexes, molecular characterization of underlying protein domains and functional evidence for their importance extend the knowledge of Wnt pathway regulation through DVL2 biomolecular condensates.
Motor units within a pool exhibit distinct rate coding as force levels change, highlighting how gain control can transform inputs with limited bandwidth into the desired muscle force.
Induction of regenerative cardiac cells (RCCs) from human embryonic stem cell-derived cardiomyocytes and neonatal rat cardiomyocytes using a novel two-compound treatment enhances heart function following myocardial infarction and offers a promising avenue for cardiac regeneration through transcriptional and epigenetic reprogramming.