Browse our latest research

Page 339 of 1,810
    1. Biochemistry and Chemical Biology

    Dual engagement of the nucleosomal acidic patches is essential for deposition of histone H2A.Z by SWR1C

    Alexander S Baier, Nathan Gioacchini ... Craig L Peterson
    Nucleosome recognition by the SWR1C chromatin remodeling enzyme requires both nucleosomal acidic patches.
    1. Neuroscience

    Reactivation strength during cued recall is modulated by graph distance within cognitive maps

    Simon Kern, Juliane Nagel ... Gordon B Feld
    Items retrieved from cognitive maps are reactivated simultaneously or sequentially depending on the performance, where in the first case the reactivation strength reflects the distance within the map.
    1. Neuroscience

    Brain representations of motion and position in the double-drift illusion

    Noah J Steinberg, Zvi N Roth ... Elisha Merriam
    The 'double-drift' illusion involves integration of retinal and non-retinal signals in the human visual cortex, providing evidence for a perceptual representation that incorporates extraretinal information.
    1. Cancer Biology
    2. Cell Biology

    mitoBKCa is functionally expressed in murine and human breast cancer cells and potentially contributes to metabolic reprogramming

    Helmut Bischof, Selina Maier ... Robert Lukowski
    A novel role of the mitochondrial BKCa channel involves the metabolic reprogramming of breast cancer cells, facilitating their unrestricted proliferation and O2-independence, which is also of potential clinical relevance.
    1. Microbiology and Infectious Disease

    A modified BCG with depletion of enzymes associated with peptidoglycan amidation induces enhanced protection against tuberculosis in mice

    Moagi Tube Shaku, Peter K Um ... Bavesh D Kana
    The new vaccine candidate for tuberculosis displays superior protection against disease when compared the currently available vaccine, and can potentially provide new options for global childhood vaccination programs.
    1. Computational and Systems Biology

    Analysis of science journalism reveals gender and regional disparities in coverage

    Natalie R Davidson, Casey S Greene
    Those quoted and mentioned in stories in Nature News mostly have names associated with men and are much less likely to have names associated with East Asia.
    1. Cancer Biology
    2. Immunology and Inflammation

    Chromosomal instability induced in cancer can enhance macrophage-initiated immune responses that include anti-tumor IgG

    Brandon H Hayes, Mai Wang ... Dennis E Discher
    Chromosomal instability induced in solid tumors can combine with macrophages that are made highly phagocytic to thereby initiate elimination of and immunity against poorly immunogenic tumors in immunocompetent mice.
    1. Microbiology and Infectious Disease

    The antigenic landscape of human influenza N2 neuraminidases from 2009 until 2017

    João Paulo Portela Catani, Anouk Smet ... Thorsten U Vogel
    N2 neuraminidases from human H3N2 viruses from 2009 until 2017 can be subdivided into four antigenic groups, with amino acid substitutions near the catalytic site more likely impacting neuraminidase inhibition.
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    ESAT-6 undergoes self-association at phagosomal pH and an ESAT-6-specific nanobody restricts M. tuberculosis growth in macrophages

    Timothy A Bates, Mila Trank-Greene ... Fikadu G Tafesse
    ESAT-6, a virulence factor of Mycobacterium tuberculosis, dimerizes at neutral pH and transitions to oligomers under acidic pH similar to that of lysosome, helping the bacterium evade host defense mechanisms.
    1. Developmental Biology

    An important role for triglyceride in regulating spermatogenesis

    Charlotte F Chao, Yanina-Yasmin Pesch ... Elizabeth Rideout
    Triglyceride plays an important role in regulating sperm development.