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Page 381 of 1,810
    1. Neuroscience

    Causal role of the angular gyrus in insight-driven memory reconfiguration

    Anna-Maria Grob, Hendrik Heinbockel ... Lars Schwabe
    Behavioral and neural analyses unravel the angular gyrus’ key role in the prioritization of integrated narratives in memory and the orchestration of theta-frequency reconfigurations underpinning the process of memory integration.
    1. Computational and Systems Biology

    What fraction of cellular DNA turnover becomes cfDNA?

    Ron Sender, Elad Noor ... Yuval Dor
    Comparing tissue-specific plasma cfDNA concentration with cellular turnover rates reveals that less than 10% of dying cells' DNA reaches plasma, highlighting significant local clearance mechanisms and suggesitng approaches to enhance liquid biopsy sensitivity.
    1. Developmental Biology
    2. Neuroscience

    A new look at the architecture and dynamics of the Hydra nerve net

    Athina Keramidioti, Sandra Schneid ... Charles N David
    A novel pan-neuronal antibody has revealed the organization of the nerve net controlling all behavior in the simple cnidarian Hydra.
    1. Chromosomes and Gene Expression

    DNA methylation-environment interactions in the human genome

    Rachel A Johnston, Katherine A Aracena ... Jenny Tung
    A massively parallel reporter assay, mSTARR-seq, reveals widespread DNA methylation-environment interactions across the genome, prioritizing CpG sites identified in epigenome-wide association studies that may be most relevant to biological embedding.
    1. Immunology and Inflammation

    RBP-J regulates homeostasis and function of circulating Ly6Clo monocytes

    Tiantian Kou, Lan Kang ... Xiaoyu Hu
    Experiments including cell and animal models investigate the molecular mechanisms underlying the regulation of homeostasis and function of monocytes.
    1. Neuroscience

    Mechanical activation of TWIK-related potassium channel by nanoscopic movement and rapid second messenger signaling

    E Nicholas Petersen, Mahmud Arif Pavel ... Scott B Hansen
    Cells utilize a membrane-mediated mechanism for mechanosensation, which involves the disruption of lipid rafts and a signal relayed to an ion channel.
    1. Computational and Systems Biology
    2. Neuroscience

    Dissecting muscle synergies in the task space

    David O'Reilly, Ioannis Delis
    A novel network information framework quantifies muscle interactions, characterises their task-relevance, and identifies networks of muscles with similar and complementary functional roles.
    1. Ecology

    Small deviations in kinematics and body form dictate muscle performances in the finely tuned avian downstroke

    Marc E Deetjen, Diana D Chin ... David Lentink
    Doves improve their wingbeat efficacy without elevating maximum pectoralis power by angling their wings mid-downstroke to efficiently generate aerodynamic force while simultaneously tensioning the supracoracoideus tendon to assist the upstroke.
    1. Cancer Biology

    Molecular classification and tumor microenvironment characteristics in pheochromocytomas

    Sen Qin, Yawei Xu ... Zheng Zhang
    ScRNA-seq of diverse pheochromocytoma patients reveals distinct microenvironment characteristics and supports an informative molecular classification system.
    1. Cancer Biology

    Large pan-cancer cell screen coupled to (phospho-)proteomics underscores high-dose vitamin C as a potent anti-cancer agent

    Andrea Vallés-Martí, Franziska Böttger ... Connie R Jiménez
    Not revised
    Reviewed Preprint v1
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