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    1. Genetics and Genomics

    Independent validation of transgenerational inheritance of learned pathogen avoidance in Caenorhabditis elegans

    Aalimah Akinosho, Joseph Alexander ... Andres Gabriel Vidal-Gadea
    Independent replication confirms that avoidance of pathogenic PA14 learned by Caenorhabditis elegans persists through the F2 generation using standardized sodium azide immobilization choice assays, clarifying prior reproducibility concerns.
    1. Ecology

    Assessing plant phenological changes based on drivers of spring phenology

    Yong Jiang, Stephen J Mayor ... Qing-Lai Dang
    A new method to partition observed phenological changes based on drivers of spring phenology has been presented.
    1. Chromosomes and Gene Expression

    Acetylation of H3K115 is associated with fragile nucleosomes at CpG island promoters and active regulatory sites

    Yatendra Kumar, Dipta Sengupta ... Wendy A Bickmore
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Biochemistry and Chemical Biology
    2. Medicine

    NAD+ boosting by oral nicotinamide mononucleotide administration regulates key metabolic and immune pathways through SIRT1 dependent and independent mechanisms to mitigate diet-induced obesity and dyslipidemia in mice

    Yasser Majeed, Najeeb M Halabi ... Nayef A Mazloum
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Neuroscience

    The inevitability and superfluousness of cell types in spatial cognition

    Xiaoliang Luo, Robert M Mok, Bradley C Love
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Incomplete
    1. Computational and Systems Biology

    Raw signal segmentation for estimating RNA modification from Nanopore direct RNA sequencing data

    Guangzhao Cheng, Aki Vehtari, Lu Cheng
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Solid
    1. Immunology and Inflammation

    Ex vivo and in vivo CRISPR/Cas9 screenings identify the roles of protein N-glycosylation in regulating T-cell activation and functions

    Yu Hong, Xiaofang Si ... Yu Zhang
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Neuroscience

    Eye-specific differences in active zone addition during synaptic competition in the developing visual system

    Chenghang Zhang, Tarlan Vatan, Colenso M Speer
    Eye-specific differences in presynaptic release site addition and clustering correlate with axonal segregation outcomes during retinogeniculate refinement in the mouse.
    1. Evolutionary Biology

    Parallel HIV-1 fitness landscapes shape viral dynamics in humans and macaques that develop broadly neutralizing antibodies

    Kai S Shimagaki, Rebecca M Lynch, John P Barton
    Fitness constraints on the HIV envelope protein are highly similar in humans and rhesus macaques, emphasizing the utility of macaque models of infection and antibody development.
    1. Developmental Biology

    A tissue boundary orchestrates the segregation of inner ear sensory organs

    Ziqi Chen, Magdalena Żak ... Nicolas Daudet
    A boundary between the sensory and nonsensory domains contains cells that undergo a series of morphological changes and form basal constriction to separate the segregating inner ear sensory organs.
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