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    1. Cell Biology
    2. Microbiology and Infectious Disease

    Decoding the biogenesis of HIV-induced CPSF6 puncta and their fusion with nuclear speckles

    Chiara Tomasini, Celine Cuche ... Francesca Di Nunzio
    HIV hijacks SRRM2 to enlarge nuclear speckles, stabilizing CPSF6 puncta and promoting efficient viral replication.
    1. Plant Biology

    Rice stripe virus utilizes a Laodelphax striatellus salivary carbonic anhydrase to facilitate plant infection by direct molecular interaction

    Jing Zhao, Xiangyi Meng ... Lili Zhang
    Planthopper salivary carbonic anhydrase enhances a plant β-1,3-glucanase to suppress callose deposition, facilitating early viral establishment of rice stripe virus.
    1. Microbiology and Infectious Disease

    Heterogeneity of genetic sequence within quasi-species of influenza virus revealed by single-molecule sequencing

    Kenji Tamao, Hiroyuki Noji, Kazuhito Tabata
    High-accuracy single-molecule unique molecular identifier sequencing reveals non-random, biologically driven mutation heterogeneity within influenza quasi-species, enabling precise profiling of intra-host viral evolutionary potential.
    1. Developmental Biology

    The livebearers platyfish and swordtails partially regenerate their hearts with persistent scarring

    Vincent Hisler, Lana Rees ... Anna Jaźwińska
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    • Convincing
    1. Neuroscience

    PKD2L1 channels segregated to the apical compartment are the exclusive dual-mode pH sensor in cerebrospinal fluid-contacting neurons

    Magdalena Vitar, Daniel Prieto ... Federico F Trigo
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Chromosomes and Gene Expression

    Fragile nucleosomes are essential for RNA Polymerase II to transcribe in eukaryotes

    Lingbo Li, Samuel Hunter ... Gongyi Zhang
    Not revised
    Reviewed Preprint v1
    • Important
    • Inadequate
    1. Genetics and Genomics
    2. Neuroscience

    Integrating bulk and single cell RNA-seq refines transcriptomic profiles of individual C. elegans neurons

    Alec Barrett, Erdem Varol ... Marc Hammarlund
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Structural Biology and Molecular Biophysics
    2. Medicine

    Direct MRI of Collagen

    Jason Daniel van Schoor, Markus Weiger ... Klaas Paul Pruessmann
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Compelling
    1. Cell Biology

    Efficiency and localisation of AURKA degradation by PROTACs is modulated by deubiquitinases UCHL5 and target-selective OTUD6A

    Annabel Cardno, Karen Roberts, Catherine Lindon
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Genetics and Genomics

    A default silencing mechanism restrains stress-induced genes in C. elegans

    Orkan Ilbay, Alejandro Rodriguez Gama ... Andrew Fire
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid