Browse our latest research

Page 717 of 1,749
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    The Shu complex prevents mutagenesis and cytotoxicity of single-strand specific alkylation lesions

    Braulio Bonilla, Alexander J Brown ... Kara A Bernstein
    The Shu complex enables lesion bypass of specific alkylation-induced DNA damage including abasic sites and 3-methyl-cytosine.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Cross-reactive antibodies after SARS-CoV-2 infection and vaccination

    Marloes Grobben, Karlijn van der Straten ... Marit J van Gils
    SARS-CoV-2 infection and vaccination elicit antibodies that cross-react with other human coronavirus spike proteins, indicating the spike S2 subdomain as a potential target strategy to develop a pan-coronavirus vaccine.
    1. Evolutionary Biology

    New fossils of Australopithecus sediba reveal a nearly complete lower back

    Scott A Williams, Thomas Cody Prang ... Lee R Berger
    Newly recovered lumbar vertebrae belonging to Malapa Hominin 2, an adult female of the fossil hominin species Australopithecus sediba, demonstrate that this individual was adapted to upright posture and bipedal locomotion but also had adaptations for climbing in trees.
    1. Cancer Biology
    2. Genetics and Genomics

    BRAFV600E induces reversible mitotic arrest in human melanocytes via microRNA-mediated suppression of AURKB

    Andrew S McNeal, Rachel L Belote ... Robert L Judson-Torres
    Oncogenic BRAF causes genome duplication and reversible growth arrest in human melanocytes that is conditional on microRNA expression and differentiation state.
    1. Cell Biology
    2. Neuroscience

    Giant ankyrin-B mediates transduction of axon guidance and collateral branch pruning factor sema 3A

    Blake A Creighton, Simone Afriyie ... Damaris N Lorenzo
    Giant ankyrin-B enables the transduction of Sema 3A repelling cues and is important for normal axonal connectivity.
    1. Cell Biology
    2. Developmental Biology

    DAAM mediates the assembly of long-lived, treadmilling stress fibers in collectively migrating epithelial cells in Drosophila

    Kristin M Sherrard, Maureen Cetera, Sally Horne-Badovinac
    Stress fibers with multiple adhesions along their lengths and treadmilling dynamics may help migrating epithelial cells maintain a linear trajectory and thereby reinforce their collective motility.
    1. Chromosomes and Gene Expression
    2. Computational and Systems Biology

    Pathway dynamics can delineate the sources of transcriptional noise in gene expression

    Lucy Ham, Marcel Jackson, Michael PH Stumpf
    There are fundamental limits to what can be learned about the origins of transcriptional noise from gene expression data alone, which can be overcome by simultaneously quantifying the abundances of linked molecular species.
    1. Developmental Biology
    2. Evolutionary Biology

    Biomarkers in a socially exchanged fluid reflect colony maturity, behavior, and distributed metabolism

    Sanja M Hakala, Marie-Pierre Meurville ... Adria C LeBoeuf
    Socially exchanged fluids passed mouth-to-mouth in ant colonies contain protein signatures of colony maturity and individual behavioral role, indicating that this fluid may underlie a distributed metabolism that functions over the scale of the colony.
    1. Microbiology and Infectious Disease

    Modeling hepatitis C virus kinetics during liver transplantation reveals the role of the liver in virus clearance

    Louis Shekhtman, Miquel Navasa ... Harel Dahari
    Very frequent viral kinetics in liver transplant patients reveals that the liver is not only the source of hepatitis C virus (HCV) production, but also plays a major role in extracellular HCV clearance.
    1. Developmental Biology
    2. Genetics and Genomics

    Quantitative spatial and temporal assessment of regulatory element activity in zebrafish

    Shipra Bhatia, Dirk Jan Kleinjan ... Wendy A Bickmore
    A new method for quantitative assessment of altered regulatory potential of human enhancers bearing disease-associated mutations using live imaging in zebrafish embryos.