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A combined developmental genetics, electrophysiology, and optical approach identify two distinct and dynamic components of the developing neuronal circuit that relay and interpret thalamic input in primary sensory neocortex.

The fast spreading of neural activity across the brain has a complex structure, imposed by the white-matter bundles.

Increases of extracellular potassium silence capillary pericyte calcium signaling, suggesting a participation of capillary pericytes in the potassium-mediated neurovascular communication.

One-step Isolation and Lysis (OIL) PCR offers a robust, versatile, accessible, and high-throughput method for linking mobile DNA with bacterial hosts in natural microbial communities.

When all features of conflicting sensory input are task-irrelevant, the brain can still process its sensory information, whereas conflict detection requires that minimally one stimulus feature is task-relevant or associated with a response.

Cell imaging and electrophysiology in the mouse hippocampus reveal a crucial role for the spatiotemporal regulation of mitochondrial dynamics in PV+ interneurons on cell morphology, network activity, and behavior.

A wild tomato species adopts local fruit color via introgression from an endemic relative, during its invasion onto the Galápagos Islands.

During neurotransmitter release, calcium-induced membrane insertion of the C2B domain of Synaptotagmin re-orients the bound SNARE complex which dilates the fusion pore in a mechanical lever action.

Mice exploring a labyrinth freely for the first time learn a complex action sequence after a handful of rewards, exhibiting a learning rate 1000-fold higher than in commonly-used paradigms.

An unbiased proteomic approach identifies a new regulator of AMPA receptor trafficking providing additional insight into synaptic transmission and plasticity.