Genome-wide CRISPR screen identified propionyl-CoA subunit B as a key regulator for anti-tumor T-cell activity in pancreatic cancer, which holds promise for advancing immunotherapy strategies in curing pancreatic cancer.
Matthew A Churgin, Danylo O Lavrentovich ... Benjamin L de Bivort
A fly’s preference for one odor versus another can be predicted by the idiosyncratic activity of neurons early on in the olfactory information processing circuit.
DLK signaling network reveals the conserved function in neuritogenesis and synapse formation, and highlights the regulation of c-Jun translation and microtubule homeostasis in hippocampal selective neuron vulnerability.
Derived from scRNA-seq, SLC26A3 is a potential therapeutic target to improve the efficacy of immunotherapy, as well as a potential diagnostic indicator to reduce post-surgical upstaging, for cervical adenocarcinoma.
