Lawrence R Frank, Vitaly L Galinsky ... Antigona Martinez
A physics-based solution to the electroencephalography (EEG) inverse problem enables whole-brain electric field imaging with high spatial and temporal resolution using standard EEG systems.
During visual search, the choice of where to look next is biased to a remarkable degree by the location and color histories of recently viewed target stimuli.
Beta synchrony between motor cortex and the subthalamic nucleus is intensified when instructional cues within a continuous motor sequence become less predictable, calling for more cautious behavior.
The combination of growth optimization and cell heterogeneity enables a quantitative explanation of overflow metabolism in microbes and the classical Warburg effect in cancer cells, resolving this long-standing puzzle.
Projection-specific optogenetic and chemogenetic experiments reveal a hippocampal-lateral septal pathway that potentially acts via the ventral tegmental area to regulate social novelty preference behaviors.
JeYoung Jung, Steve Williams, Matthew A Lambon Ralph
GABAergic inhibition in the anterior temporal lobe shapes semantic memory and its neuroplasticity through a non-linear relationship, revealing a neurochemical basis for individual differences.
Drug synergy Interaction Prediction improves personalized drug synergy prediction by utilizing drug-specific pathway activation scores to predict personalized drug synergy and reveals mechanistic pathways underlying synergistic effects.
Functional analyses reveal the HNF4α-TET2-FBP1 axis as a critical regulator of gluconeogenesis, type 2 diabetes (T2D) progression, and metformin’s therapeutic effects, which proposes TET2 as a promising therapeutic target for T2D.
