Browse our Research Articles

A systematic review shows no evidence of harm or benefit of antibiotic combinations on resistance evolution as clinical data lack statistical power to draw definitive conclusions, highlighting a knowledge gap.

The inclusive, exclusive, and hierarchical atlas of NFATc1⁺/PDGFR-α⁺ cells in dental and periodontal mesenchyme is described.

A principle from which the neuronal dynamics and synaptic plasticity in arbitrary network architectures can be inferred, so that output errors are online minimized while simultaneously processing sensory input streams.

Mutagenizing sequences enriched with promoter motifs creates gene expression de novo, and helps to understand promoter logic, regulatory evolution, and the birth of de novo genes.

Mitochondrial respiration atlas reveals functional signatures of aging across diverse tissues and organ systems.

A novel molecular mechanism linking a neurotrophin with a Toll-family and kinase-less Trk-like receptors provides a direct link from molecules to structural circuit plasticity and modification of behaviour.

A new method to infer the spatial history of genetic ancestors from a sequence of trees along a recombining genome.

Aphid and mildew read counts leftover from the sequencing of greenhouse plants correlated with the environment of origin of the plants, and allowed the mapping of pathogen resistance genes.

The inhibition of colorectal cancer (CRC) proliferation, migration, and invasion is attributed to BEST4, which exhibits epistasis over Hes4 in the downregulation of Twist1 and consequent suppression of epithelial-to-mesenchymal transition in CRC.

Analysis of genome-wide spatial transcriptomics data reveals cell-type specific subcellular RNA localization, and a subset of genes show significantly high correlation between spatial patterning and 3' UTR length.