Browse our Research Articles

In sturgeon, fewer electrosensory organs form after targeting Bmp5 for CRISPR/Cas9-mediated mutagenesis, whereas more form after chemically blocking all Bmp signalling shortly before their primordia emerge, suggesting that Bmp signalling has opposing effects during electrosensory organ development.

Jyvaskylavirus, the northernmost isolate of the Marseilleviridae family, shows that giant viruses are also part of the boreal Finnish environment and brings structural information with relevance for understanding other viruses.

Oxidized LDL synergizes with angiotensin II to amplify Gq signaling via the AT1-LOX1 receptor complex, revealing a novel mechanism driving renal dysfunction in hypertension and dyslipidemia.

Oncogene permanent activation in a single targeted cell of zebrafish together with a reprogramming factor transient activation is sufficient to induce the malignant transformation of the cell and tumor development.

Characterization of nuclear pore loss and dysfunction in nucleocytoplasmic compartmentalization in Alzheimer's disease neurons.

Mice lacking the secreted hormone, CTRP10, represent a unique female model of obesity with preserved metabolic health, highlighting sex-specific mechanisms that uncouple obesity from metabolic dysfunction.

Hippocampal replay, which is implicated in memory formation and planning, exhibits a reward-dependent spatial specificity that in novel environments requires dopamine signaling.

ORMDL3 promotes RIG-I degradation to suppress type I interferon signaling pathway and antiviral immune response, highlighting ORMDL3 as a potential therapeutic target in viral infection and cancer immunotherapy.

Neurobehavioral data combined with computational models shows the superiority of active inference models in explaining human decisions under uncertainty.

A multiomic study reveals the role of ZFHX3 transcription factor in daily timekeeping with a combination of transcription factor and histone ChIP-seq and time-resolved RNA-seq in the mammalian central clock.