Browse our Research Articles

The morphogenesis of brain folding patterns across species is studied by physical gel models, simulations, and a quantitative morphometric analysis.

ANKEF1 stabilizes the sperm axoneme by reinforcing the nexin–dynein regulatory complex, revealing a mechanical buffering mechanism essential for flagellar integrity and male fertility.

Transcriptomic and metabolite analysis reveal sex differences in circulation and excretion of bile acids in a mouse- model of hepatocellular carcinoma (HCC), and the identified female-specific gene profile correlates with better HCC survival.

Loss of class A scavenger receptor MARCO results in elevated lung Ace expression and elevated plasma aldosterone concentrations in male mice, demonstrating an endocrine function of this immune scavenger receptor.

PLSCR1 is an IFN-λ-stimulated gene that enhances IFN-λR1 expression at both transcriptional and protein level, highlighting the potential for targeting PLSCR1 pathways in anti-influenza therapy.

CpG density and epigenetic modification state modulate DNA mechanics, altering its intrinsic compatibility with nucleosome formation.

Nonlinear dendritic integration in single presubicular neurons provides a mechanism for combining vestibular-based head-direction signals and visual landmark signals to anchor the brain’s internal compass.

In mice, loss of TGF-beta signaling specifically in vascular endothelial cells leads to retinal hypovascularization, choroidal neovascularization, a pro-inflammatory state within brain and retinal endothelial cells, and an influx of diverse inflammatory cells into the retina.

Oligodendrocytes with different morphological features work together to support precise binaural integration for sound localization in the chick brainstem auditory circuit.

An evolutionarily conserved glycosphingolipid metabolite ensures precise stem cell fate decisions by modulating Delta-Notch signaling dynamics.