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Esr1 directs adolescent transcriptional maturation of medial preoptic GABAergic neurons, enabling the normal development of mating behavior in male and female mice.

A multi-step ribosome assembly method involving changes in ion concentration and temperature can now be carried out in a single step using the two GTPase factors, EngA and ObgE.

A genetic analysis in yeast establishes that multicellularity can arise as a side-effect (passenger phenotype) of a completely independent fitness advantage unrelated to the benefits of group formation itself.

Enterovirus D68, a cause of acute flaccid myelitis, disrupts the composition and function of the nuclear pore complex primarily through its 2A protease, which is also toxic to motor neurons.

Disrupting oligodendrocytes during a narrow early-life window leaves cerebellar circuits permanently mistimed, but adult re-synchronization restores social and motor behavior.

Presynaptic endocytic machinery is constitutively deployed to periactive zones, indicating independent assembly pathways for the exo- and endocytic machineries of nerve terminals.

Cellular mechanotransmission depends on nuclear lamina composition, where A-type and B-type lamins define distinct nuclear mechanical responses, and microtubules dynamically buffer intracellular tension.

Terminal tracheal cells in Drosophila evade innate immune activation, revealing a fundamental trade-off in which suppression of canonical immune signaling preserves Foxo-dependent plasticity and sustains respiratory function.

Analyses of two independent phylogenomic datasets suggest an explosive radiation at the origin of Spiralia, with implications for understanding the group's evolutionary history.

Linear or categorical activity from neurons in the gustatory cortex is necessary for network dynamics and performance.