Browse our Research Articles

Page 24 of 1,444
    1. Cell Biology

    SARS-CoV-2 NSP13 interacts with TEAD to suppress Hippo-YAP signaling

    Fansen Meng, Jong Hwan Kim ... James F Martin
    A novel YAP/TEAD regulatory mechanism by NSP13 provides molecular insights into Hippo-YAP regulation after SARS-CoV-2 infection.
    1. Neuroscience

    Hierarchical encoding of natural sound mixtures in ferret auditory cortex

    Agnès Landemard, Célian Bimbard, Yves Boubenec
    To parse foreground and background sounds, the auditory cortex of humans and ferrets share a similar hierarchical organization, but the underlying computational mechanisms are fundamentally different.
    1. Neuroscience

    Restoration of locomotor function following stimulation of the A13 region in Parkinson’s mouse models

    Linda H Kim, Adam Lognon ... Patrick J Whelan
    Stimulation of the A13 brain region restores motor function in Parkinson's disease mouse models by alleviating bradykinesia and akinesia.
    1. Cell Biology
    2. Developmental Biology

    Sulfation affects apical extracellular matrix organization during development of the Drosophila embryonic salivary gland tube

    J Luke Woodward, Jeffrey Matthew ... SeYeon Chung
    Sulfation is required for organizing the apical extracellular matrix during tubular organ formation.
    1. Microbiology and Infectious Disease

    The increase in cell volume and nuclear number of the koji-fungus Aspergillus oryzae contributes to its high enzyme productivity

    Ayaka Itani, Haruto Motomura ... Norio Takeshita
    More nuclei and cell volume, more enzymes in koji-fungus Aspergillus oryzae.
    1. Neuroscience

    Rab10 inactivation promotes AMPAR trafficking and spine enlargement during long-term potentiation

    Jie Wang, Jun Nishiyama ... Ryohei Yasuda
    Rab10 and Rab4 bidirectionally regulate AMPA receptor trafficking and spine structural plasticity during long-term potentiation by exhibiting opposing and temporally distinct activity patterns in stimulated dendritic spines.
    1. Computational and Systems Biology
    2. Neuroscience

    Neural dynamics of reversal learning in the prefrontal cortex and recurrent neural networks

    Christopher M Kim, Carson C Chow, Bruno B Averbeck
    Neural activity during reversal learning encodes decision-related evidence integrated across trials and shows substantial dynamics during each trial, suggesting an extension of the line attractor model that incorporates non-stationary dynamics.
    1. Neuroscience

    Oxytocin restores context-specific hyperaltruistic preference

    Hong Zhang, Yinmei Ni, Jian Li
    Oxytocin facilitates hyperaltruism by promoting harm-framing in the moral decision-making task.
    1. Microbiology and Infectious Disease

    A SHERLOCK toolbox for eco-epidemiological surveillance of African trypanosomes in domestic pigs from Western Africa

    Roger Eloiflin, Elena Pérez-Antón ... Brice Rotureau
    A novel array of CRISPR-based SHERLOCK tests for RNA detection was developed for eco-epidemiological surveillance of human and animal African trypanosomes from Western Africa with domestic pigs as sentinels.
    1. Computational and Systems Biology

    Identification of type 2 diabetes- and obesity-associated human β-cells using deep transfer learning

    Gitanjali Roy, Rameesha Syed ... Michael A Kalwat
    Deep transfer learning methodologies reveal hidden heterogeneity in β-cells driven by type 2 diabetes and obesity.