Browse our Research Articles

Page 24 of 1,441
    1. Cancer Biology

    SETD2 suppresses tumorigenesis in a KRASG12C-driven lung cancer model, and its catalytic activity is regulated by histone acetylation

    Ricardo J Mack, Natasha M Flores ... Or Gozani
    Genetic and biochemical studies show that SETD2 is tumor suppressive in a lung cancer mouse model and SETD2 methylation activity in vitro is regulated by histone acetylation.
    1. Cell Biology
    2. Evolutionary Biology

    Horizontally transferred cell-free chromatin particles function as autonomous ‘satellite genomes’ and vehicles for transposable elements within host cells

    Soumita Banerjee, Soniya Sanjay Shende ... Indraneel Mittra
    Uptake of cell-free chromatin particles released from dying cells and carrying non-coding DNA could redefine mammalian genomics.
    1. Structural Biology and Molecular Biophysics

    Crosslinking by ZapD drives the assembly of short FtsZ filaments into toroidal structures in solution

    Adrián Merino-Salomón, Jonathan Schneider ... Germán Rivas
    Promoting FtsZ toroidal polymer formation by ZapD offers new insights into stabilizing the bacterial division ring.
    1. Evolutionary Biology

    The general version of Hamilton’s rule

    Matthijs van Veelen
    The flexibility of the general version of Hamilton's rule allows the rule to match the complexity of the model of social behaviour, or the complexity implied by the data.
    1. Neuroscience

    Policy shaping based on the learned preferences of others accounts for risky decision-making under social observation

    HeeYoung Seon, Dongil Chung
    Simulating others' preferences underlies riskier choices when being observed, driven by beliefs about observers' risk attitudes and supported by TPJ–dmPFC connectivity.
    1. Cell Biology
    2. Developmental Biology

    Gene regulatory mechanisms guiding bifurcation of inhibitory and excitatory neuron lineages in the mouse anterior brainstem

    Sami Kilpinen, Lassi Virtanen ... Juha Partanen
    Changes of the chromatin structure suggests how the fate selector transcription factors are activated and how they guide differentiation of GABAergic and glutamatergic neurons in the anterior brainstem.
    1. Neuroscience

    Sequence action representations contextualize during early skill learning

    Debadatta Dash, Fumiaki Iwane ... Leonardo G Cohen
    When learning a new skill, neural representations of individual actions rapidly incorporate contextual information pertaining to the encompassing skill sequence-primarily during rest breaks interleaved with practice.
    1. Neuroscience

    The spatial frequency representation predicts category coding in the inferior temporal cortex

    Ramin Toosi, Behnam Karami ... Mohammad-Reza A Dehaqani
    Spatial frequency is explicitly and dynamically represented in the primate inferior temporal cortex, revealing distinct neural populations that differentially support object recognition, specially emphasizing high-frequency contributions to face processing.
    1. Microbiology and Infectious Disease

    Tuberculosis susceptibility in genetically diverse mice reveals functional diversity of neutrophils

    Marietta M Ravesloot-Chavez, Erik Van Dis ... Sarah A Stanley
    Wild-derived mice exhibit diversity in outcomes after infection with Mycobacterium tuberculosis.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Ancient trans-species polymorphism at the Major Histocompatibility Complex in primates

    Alyssa Lyn Fortier, Jonathan K Pritchard
    Trans-species polymorphism at primate Major Histocompatibility Complex genes is old, especially in the 'classical' genes, while rapidly-evolving regions of each gene correspond with proteins' functional domains.