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These findings provide convincing evidence of the beneficial effects that restored biological rhythms may have on disease pathophysiology and symptoms.

Grafting surface loops containing antibody epitopes of a poorly expressed flu neuraminidase protein onto a high-expressing, stable scaffold improves its production and stability for vaccine development.

In ovo light exposure that induces brain lateralization boosts chicks' number sense and spatial-numerical association.

A hitherto unrecognized superfamily of enzymes identified here provides unifying insights spanning lipid metabolism, anti-viral and anti-bacterial immunity, and the origin of developmental regulators like Wnt.

Inhibition of the endothelin B receptor (ETBR) with FDA-approved Bosentan enhances axon regeneration and reverses age-related decline, revealing a promising therapeutic target for improving nerve repair in older individuals.

Gut-to-brain communication via glial cytokine signaling links intestinal oxidative stress to altered sleep patterns, highlighting how gut inflammation can influence brain function and restorative sleep behaviors essential for mental well-being.

Discovery of calcarins in calcareous sponges highlights gene duplication and neofunctionalization as drivers of parallel biomineralization, offering insight into the independent evolution of calcification in early-diverging animals.

fMRI decoding reveals that the inferior frontal junction-visual network reinstates target-related information as a proxy for target localization before visual search.

The kinase activity of Aurora kinase A is required for preserving S-adenosylmethionine availability for histone methylation and epigenetic reprogramming during trained immunity induction in macrophages.

The crystal structure of Sld3CBD-Cdc45 shows its intermolecular interactions, and subsequent Sld3CBD-CMG model construction and binding assays enable a proposal for the mechanism of Cdc45 recruitment and Sld3 release.