Analysis of monoclonal immunoglobulin A (IgA) antibodies after intranasal immunization highlights the crucial role of secretory IgA in mucosal immunity, enhancing our understanding of how intranasal vaccines can protect against SARS-CoV-2 infection.
Karen Giménez-Orenga, Eva Martín-Martínez ... Elisa Oltra
Transcriptomic profiling of HERV elements at the loci level differentiates ME/CFS, fibromyalgia, and their overlap, revealing distinct immuno-epigenetic landscapes.
A cross-talk is revealed between two branches of metabolisms, amino acid limitation suppressing fatty acid biosynthesis, via posttranslational modifications of an enzyme involved in fatty acid biosynthesis.
MARK2-mediated phosphorylation of CAMSAP2 dynamically controls Golgi orientation by altering microtubule anchoring and polarity during directional cell migration.
Gene expression in nematodes during cold-induced dormancy is proposed to be regulated at the transcription level, partly involving the activation of unfolded protein response (UPR) through the IRE-1/XBP-1 signaling pathway.
Simon Rethemeier, Sonja Fritzsche ... Vera S Hunnekuhl
Genetic labeling and molecular analyses characterize the dynamics of embryonic central complex-forming type II neuroblast lineages in Tribolium castaneum.
Sakshi Shambhavi, Sudipta Mondal ... Rajan Sankaranarayanan
Dip2 regulates PKC signalling through specific DAG acyl chain compositions—a crucial pathway, which emerged approximately 1.2 billion years ago, marking the advent of selective DAG-based signalling in eukaryotes.