Browse our Research Articles

Page 24 of 1,508
    1. Developmental Biology
    2. Genetics and Genomics

    In situ mutational screening and CRISPR interference define apterous cis-regulatory inputs during compartment boundary formation

    Gustavo Aguilar, Michèle E Sickmann ... Martin Müller
    Early enhancer logic precisely aligns developmental boundaries by integrating HOX, GATA, and signaling inputs, ensuring correct tissue patterning and preventing mirror-image duplications in the developing wing.
    1. Neuroscience

    Sexual dimorphism in sensorimotor transformation of optic flow

    Sarah Nicholas, Katja Sporar Klinge ... Karin Nordström
    Descending neurons that encode widefield motion vision in the fly have sexually dimorphic velocity tuning, while the wing beat amplitude, which these neurons presumably control, is monomorphic.
    1. Neuroscience

    Involuntary feedback responses reflect a representation of partner actions

    Seth R Sullivan, John H Buggeln ... Joshua GA Cashaback
    High-level partner representations tune low-level visuomotor reflexes.
    1. Ecology

    Developmental constraints mediate the reversal of temperature effects on the autumn phenology of European beech after the summer solstice

    Dominic Rebindaine, Thomas W Crowther ... Constantin M Zohner
    Faster early-season development, especially under nighttime warming, advances the point at which the autumn phenology of European beech becomes responsive to late-summer cooling.
    1. Developmental Biology

    Single-cell transcriptomics-informed induced pluripotent stem cells differentiation to tenogenic lineage

    Angela Papalamprou, Victoria Yu ... Dmitriy Sheyn
    Exploring the differentiation of iPSC to trunk tenocytes and how the single-cell RNA sequencing and pathway analysis can assist in making it more specific.
    1. Immunology and Inflammation

    Lipopolysaccharide stimulates dynamic changes in B cell metabolism to promote proliferation

    Dana MS Cheung, Momchil Razsolkov ... J Simon C Arthur
    B cell activation and antibody class switching requires coordinated metabolic rewiring, with essential roles for amino acid transport, cholesterol metabolism, and prenylation in driving proliferation across multiple activating stimuli.
    1. Neuroscience

    The nucleus accumbens shell regulates hedonic feeding via a rostral hotspot

    Alina-Măriuca Marinescu, Eshita Kamal ... Marie A Labouesse
    Within the nucleus accumbens shell, a spatially defined rostral subregion selectively modulates hedonic feeding, revealing functional heterogeneity in reward circuitry underlying food consumption.
    1. Biochemistry and Chemical Biology
    2. Chromosomes and Gene Expression

    MORC2 mediates transcriptional regulation through liquid-liquid phase separation

    Yanshen Zhang, Weiya Xu ... Yihui Bi
    The dynamic internal fluidity of nuclear MORC2 condensates, rather than their mere assembly, is strictly required for transcriptional regulation and is selectively disrupted by neuropathy-linked mutations.
    1. Cell Biology

    The multifaceted role of EXOC6A in ciliogenesis

    Te-Lin Lin, Chien-Ting Wu, Tang K Tang
    EXOC6A cooperates with myosin-Va to regulate vesicle trafficking and membrane remodeling during ciliogenesis, enabling ciliary vesicle maturation, transition zone assembly, and proper delivery of ciliary membrane proteins.
    1. Neuroscience

    Multimodal MRI marker of cognition explains the association between cognition and mental health in the UK Biobank

    Irina Buianova, Mateus Silvestrin ... Narun Pat
    Multimodal stacking of MRI‑based markers of cognition reveals a shared brain architecture that links cognitive performance with mental health, explaining nearly half of their observed association.