Browse our Research Articles

Page 295 of 1,390
    1. Physics of Living Systems

    Motor processivity and speed determine structure and dynamics of microtubule-motor assemblies

    Rachel A Banks, Vahe Galstyan ... Rob Phillips
    Mesoscopic properties of motor-microtubule assemblies, such as contractile rates and length scales, can be quantitatively connected to single-motor properties of kinesin motors.
    1. Cell Biology
    2. Computational and Systems Biology

    Information transfer in mammalian glycan-based communication

    Felix F Fuchsberger, Dongyoon Kim ... Christoph Rademacher
    The information stored in glycans is interpreted and read by cell surface-exposed lectin receptors, and with information theory, the formal framework is set for how to analyze such complex single-cell data.
    1. Medicine

    Cardiac electrophysiological remodeling associated with enhanced arrhythmia susceptibility in a canine model of elite exercise

    Alexandra Polyák, Leila Topal ... András Varró
    Vigorous endurance training results in prolongation of cardiac repolarization and increased repolarization instability, mild ventricular fibrosis associated with decrease of the transient outward potassium current, and enhanced arrhythmia susceptibility in canine model.
    1. Neuroscience

    SUMOylation of NaV1.2 channels regulates the velocity of backpropagating action potentials in cortical pyramidal neurons

    Oron Kotler, Yana Khrapunsky ... Ilya Fleidervish
    In cortical pyramidal neurons, subtype-specific SUMOylation of Na+ channels regulates input-output relationships, synaptic boosting, and action potential propagation from the axonal trigger zone back into the dendrites.
    1. Neuroscience

    Neural circuits underlying habituation of visually evoked escape behaviors in larval zebrafish

    Haleh Fotowat, Florian Engert
    A novel neural mechanism is proposed and validated in larval zebrafish to explain how animals habituate to repeated looming stimulation.
    1. Immunology and Inflammation

    Fever integrates antimicrobial defences, inflammation control, and tissue repair in a cold-blooded vertebrate

    Farah Haddad, Amro M Soliman ... Daniel R Barreda
    Behavioural, molecular, and functional analyses revealed that fever contributes to induction and resolution phases of acute inflammation, through enhancement of antimicrobial defences, increased efficiency in inflammation control, and improved wound repair.
    1. Neuroscience

    A transcriptional constraint mechanism limits the homeostatic response to activity deprivation in mammalian neocortex

    Vera Valakh, Derek Wise ... Sacha B Nelson
    For the first time, the strength of homeostatic plasticity has been shown to be negatively regulated and the transcription factors responsible for this regulation have been identified.
    1. Physics of Living Systems

    Emergent periodicity in the collective synchronous flashing of fireflies

    Raphael Sarfati, Kunaal Joshi ... Orit Peleg
    1. Cell Biology

    Meisosomes, folded membrane microdomains between the apical extracellular matrix and epidermis

    Dina Aggad, Nicolas Brouilly ... Nathalie Pujol
    Combining live imaging and advanced electron microscopy gives insights into the structural integrity of the nematode epidermis and its intimate connection with the extracellular matrix.
    1. Cell Biology

    Synergistic stabilization of microtubules by BUB-1, HCP-1, and CLS-2 controls microtubule pausing and meiotic spindle assembly

    Nicolas Macaisne, Laura Bellutti ... Julien Dumont
    Promotion of microtubule pausing by a kinetochore module controls meiotic spindle assembly in Caenorhabditis elegans oocytes.