Browse our Research Articles

Page 580 of 1,486
    1. Cell Biology

    Acetyl-CoA production by specific metabolites promotes cardiac repair after myocardial infarction via histone acetylation

    Ienglam Lei, Shuo Tian ... Zhong Wang
    An acetyl-CoA-mediated metabolic and epigenetic network has been elucidated that stimulates histone acetylation and anti-oxidative stress gene expression for heart repair after myocardial infarction.
    1. Structural Biology and Molecular Biophysics

    A modular platform for automated cryo-FIB workflows

    Sven Klumpe, Herman KH Fung ... Julia Mahamid
    SerialFIB is an adaptable open-source software designed for streamlining, advanced development and automation of cryo-focused ion beam-based cellular preparations for in situ cryo-electron tomography.
    1. Neuroscience

    Respiration aligns perception with neural excitability

    Daniel S Kluger, Elio Balestrieri ... Joachim Gross
    Noninvasive human magnetoencephalography recordings characterize the functional relationship between respiration, neural oscillations, and performance in low-level perception.
    1. Neuroscience

    Structure and function of axo-axonic inhibition

    Casey M Schneider-Mizell, Agnes L Bodor ... Nuno Maçarico da Costa
    Electron microcopy-based connectomics, in vivo functional imaging, and biophysical modeling reveal that mouse visual cortex chandelier cells, a type of GABAergic interneuron, are driven by arousal and distribute their synapses according to the individual properties of target cells.
    1. Cell Biology
    2. Structural Biology and Molecular Biophysics

    Determinants shaping the nanoscale architecture of the mouse rod outer segment

    Matthias Pöge, Julia Mahamid ... Wolfgang Baumeister
    Cryo-electron tomography of close-to-native rod outer segments resolves connectors between disks and a scaffold at the disk rim enforcing the high membrane curvature of the unique long-range organization in these rhodopsin-rich light-sensitive subcellular organelles.
    1. Neuroscience

    Dopamine enhances model-free credit assignment through boosting of retrospective model-based inference

    Lorenz Deserno, Rani Moran ... Raymond J Dolan
    Cooperation between model-free and model-based control systems is boosted by enhancing dopamine levels.
    1. Developmental Biology
    2. Neuroscience

    insomniac links the development and function of a sleep-regulatory circuit

    Qiuling Li, Hyunsoo Jang ... Nicholas Stavropoulos
    Spatiotemporal manipulations of insomniac reveal that this gene regulates the birth and development of sleep-regulatory neurons, enabling their proper function in adulthood.
    1. Physics of Living Systems

    Strong confinement of active microalgae leads to inversion of vortex flow and enhanced mixing

    Debasmita Mondal, Ameya G Prabhune ... Prerna Sharma
    Coupling between cell motility and strong confinement alters the force generators that cause flow fields to change their handedness and lead to enhanced mixing.
    1. Biochemistry and Chemical Biology
    2. Neuroscience

    Neurotoxin-mediated potent activation of the axon degeneration regulator SARM1

    Andrea Loreto, Carlo Angeletti ... Michael P Coleman
    The identification of the mechanism of action of vacor, an environmental neurotoxin which causes neurodegeneration by activating the pro-degenerative enzyme SARM1, raises important questions on SARM1 as a mediator of environmental neurotoxicity and has implications for drug discovery.
    1. Cell Biology
    2. Immunology and Inflammation

    Robust T cell activation requires an eIF3-driven burst in T cell receptor translation

    Dasmanthie De Silva, Lucas Ferguson ... Jamie HD Cate
    Binding of the translation initiation factor eIF3 to the messenger RNAs encoding the T cell receptor subunits alpha and beta is required to drive a short burst in their translation and promote a strong T cell response.