Browse our Research Articles

Page 594 of 1,272
    1. Computational and Systems Biology
    2. Physics of Living Systems

    Social interactions drive efficient foraging and income equality in groups of fish

    Roy Harpaz, Elad Schneidman
    Analysis and modeling of group behavior of adult zebrafish shows that a specialized social interaction mechanism increases foraging efficiency and equality within groups, under a variety of environmental conditions.
    1. Structural Biology and Molecular Biophysics

    Structural basis for histone variant H3tK27me3 recognition by PHF1 and PHF19

    Cheng Dong, Reiko Nakagawa ... Jinrong Min
    Complex structures of Tudor domains of PHF1/19 with H3tK27me3 provide structural basis for preferential recognition of H3tK27me3 over canonical H3K27me3, implicating that H3tK27me3 might be a physiological ligand of PHF1/19.
    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    Mutational resilience of antiviral restriction favors primate TRIM5α in host-virus evolutionary arms races

    Jeannette L Tenthorey, Candice Young ... Harmit S Malik
    Mutations in the TRIM5α retrovirus-binding interface frequently improve but rarely disrupt retroviral restriction.
    1. Neuroscience

    Efficient sampling and noisy decisions

    Joseph A Heng, Michael Woodford, Rafael Polania
    An efficient coding theory for higher-level cognitive processes reveals that humans efficiently adapt to contextual distributions by economizing on environmental prior information.
    1. Biochemistry and Chemical Biology

    Transport of DNA within cohesin involves clamping on top of engaged heads by Scc2 and entrapment within the ring by Scc3

    James E Collier, Byung-Gil Lee ... Kim A Nasmyth
    Rigorous biochemical and structural analyses reveal the precise topology of cohesin's association with DNA and suggest a mechanism for how DNA is transported inside the ring.
    1. Ecology
    2. Epidemiology and Global Health

    Transmission of West Nile and five other temperate mosquito-borne viruses peaks at temperatures between 23°C and 26°C

    Marta S Shocket, Anna B Verwillow ... Erin A Mordecai
    Mechanistic, trait-based models for transmission of West Nile virus and observed incidence of human West Nile disease cases in the US both show optimal transmission at 24-25°C.
    1. Neuroscience

    An essential role for MEF2C in the cortical response to loss of sleep in mice

    Theresa E Bjorness, Ashwinikumar Kulkarni ... Robert W Greene
    The transcription factor, MEF2C, mediates a change in approximately one half of the expressed frontal cortical transcriptome controlling cellular metabolism and synaptic strength in response to acute loss of sleep.
    1. Neuroscience

    Mesoscopic-scale functional networks in the primate amygdala

    Jeremiah K Morrow, Michael X Cohen, Katalin M Gothard
    Multivariate data decomposition applied to local field potentials recorded from the primate amygdala revealed simultaneously active and functionally distinct networks, defined by anatomical boundaries between the nuclei.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Puromycin reactivity does not accurately localize translation at the subcellular level

    Syed Usman Enam, Boris Zinshteyn ... Rachel Green
    Methods that use puromycin to localize active translation do not actually detect the site of translation.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Elongation inhibitors do not prevent the release of puromycylated nascent polypeptide chains from ribosomes

    Benjamin D Hobson, Linghao Kong ... Peter A Sims
    Although puromycin staining is often used to examine subcellular translation, puromycin-labeled proteins are rapidly released from ribosomes even in the presence of elongation inhibitors, which may confound translation site localization.