Browse our Research Articles

Page 627 of 1,477
    1. Cell Biology
    2. Immunology and Inflammation

    Endothelial junctional membrane protrusions serve as hotspots for neutrophil transmigration

    Janine JG Arts, Eike K Mahlandt ... Jaap D van Buul
    Neutrophils use dorsal membrane protrusions of endothelial cells to cross the vascular wall.
    1. Structural Biology and Molecular Biophysics

    Hsp40s play complementary roles in the prevention of tau amyloid formation

    Rose Irwin, Ofrah Faust ... Rina Rosenzweig
    Chaperones from different families and classes synergistically target different stages of tau aggregation, thus preventing pathological amyloid formation.
    1. Plant Biology
    2. Structural Biology and Molecular Biophysics

    In situ cryo-ET structure of phycobilisome–photosystem II supercomplex from red alga

    Meijing Li, Jianfei Ma ... Sen-Fang Sui
    The nature of the phycobilisome–photosystem II supercomplex on the native thylakoid determined with cryo-electron tomography at an unprecedented resolution reveals that one phycobilisome interconnects with six photosystem monomers.
    1. Microbiology and Infectious Disease

    Interferon receptor-deficient mice are susceptible to eschar-associated rickettsiosis

    Thomas P Burke, Patrik Engström ... Matthew D Welch
    Type I interferon and interferon-γ signaling redundantly protects mice from the tick-borne pathogen Rickettsia parkeri in the skin, and interferon receptor-deficient mice are a tractable model for investigating rickettsiosis.
    1. Evolutionary Biology

    Evolution of diversity in metabolic strategies

    Rodrigo Caetano, Yaroslav Ispolatov, Michael Doebeli
    Analytical and numerical analyses reveal that the number of coexisting species exceeds the number of resource only for the structurally unstable case of linear tradeoff.
    1. Plant Biology
    2. Structural Biology and Molecular Biophysics

    The structure of photosystem I from a high-light-tolerant cyanobacteria

    Zachary Dobson, Safa Ahad ... Yuval Mazor
    The necessity of studying extremophile organisms is exemplified by the structure of photosystem I from a high-light tolerant cyanobacteria, demonstrating the relationship between the structure and function in photosystem I.
    1. Neuroscience

    The corticospinal tract primarily modulates sensory inputs in the mouse lumbar cord

    Yunuen Moreno-Lopez, Charlotte Bichara ... Matilde Cordero-Erausquin
    While the corticospinal tract is often considered exclusively as a motor path, a combination of intersectional viral strategy and in vivo electrophysiology reveals that, in the mouse lumbar cord, its main role is the modulation of sensory inputs.
    1. Cell Biology
    2. Neuroscience

    The amyloid precursor protein is a conserved Wnt receptor

    Tengyuan Liu, Tingting Zhang ... Bassem A Hassan
    The amyloid precursor protein known for its role in causing familial Alzheimer's disease directly interacts with secreted proteins, called Wnts, known for their key roles in brain development and homeostasis, suggesting the two processes may be directly linked.
    1. Genetics and Genomics
    2. Neuroscience

    Neuronal calmodulin levels are controlled by CAMTA transcription factors

    Thanh Thi Vuong-Brender, Sean Flynn ... Mario de Bono
    CAMTA transcription factors are evolutionarily conserved regulators of neuronal levels of the major Ca2+ sensor calmodulin.
    1. Developmental Biology
    2. Neuroscience

    Large-scale phenotypic drug screen identifies neuroprotectants in zebrafish and mouse models of retinitis pigmentosa

    Liyun Zhang, Conan Chen ... Jeff S Mumm
    Using a cross-species phenotypic drug discovery pipeline, compounds promoting rod photoreceptor survival in zebrafish and mouse models of retinitis pigmentosa were identified, evidence of additive effects of paired compounds and inhibition of PARP-dependent cell death suggest novel therapeutic strategies.