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Social dominance has opposing effects on behavior following stress in male vs. female mice indicating an important role in sex differences in the stress response.

Hedgehog acts as a morphogen by regulating proteolytic processing and activation of full-length Ci/Gli transcriptional effectors but can pattern Drosophila wing discs normally in the absence of regulated proteolytic processing.

Mucosal-associated invariant T (MAIT) cells, highly activated and dysfunctional in sepsis patients, contribute to tissue-specific cytokine responses that are protective against mortality during experimental sepsis.

Single molecule FISH analysis defines the behavior of centromere-derived alpha-satellite transcripts in intact human cells and reveals a critical role for centromere-nucleolar contacts in repressing alpha-satellite transcription.

Depletion of LRRC8A provides genetic evidence for the importance of Cl^- channels in NLRP3 activation.

Activity-dependent genetic labeling during behavioral learning shows Fragile-X syndrome model mice exhibit impaired hippocampal engram reactivation, and that enriched environment experience improves fear memory retrieval by enhancing engram reactivation efficacy.

Hierarchical information flow in a cortico-limbic loop between the insular cortex, central amygdala and the cholinergic basal forebrain links bodily states with environmental stimuli to guide fear and reward behavior.

Conscious visual percepts are encoded by face patches in the absence of report, can be decoded from population recordings, and are multiplexed with the veridical physical stimulus.

SUMO-dependent pathway is responsible for selective repression of damaged rDNA and silencing of intact surplus units revealing an epigenetic mechanism that controls the differential expression of identical sequences in the same cell.

miR-17~92 family of miRNAs control the balance between pro- and anti-inflammatory cytokines in adipose tissue macrophages, the absence of which leads to disturbed adipose homeostasis.