Browse our Research Articles

Page 716 of 1,424
    1. Immunology and Inflammation

    MicroRNAs of the miR-17~92 family maintain adipose tissue macrophage homeostasis by sustaining IL-10 expression

    Xiang Zhang, Jianguo Liu ... Xiaoyu Hu
    miR-17~92 family of miRNAs control the balance between pro- and anti-inflammatory cytokines in adipose tissue macrophages, the absence of which leads to disturbed adipose homeostasis.
    1. Plant Biology

    The genetic architecture of host response reveals the importance of arbuscular mycorrhizae to maize cultivation

    M Rosario Ramírez-Flores, Sergio Perez-Limon ... Ruairidh JH Sawers
    Heritable variation in the benefit maize plants receive from arbuscular mycorrhizal fungi supports the feasibility of breeding crops to optimize use of this ancient symbiosis.
    1. Computational and Systems Biology
    2. Neuroscience

    Bayesian inference for biophysical neuron models enables stimulus optimization for retinal neuroprosthetics

    Jonathan Oesterle, Christian Behrens ... Philipp Berens
    Bayesian simulator-based inference is used to infer the parameters of complex multicompartment models of retinal neurons from two-photon imaging data.
    1. Cell Biology
    2. Immunology and Inflammation

    Wiskott Aldrich syndrome protein regulates non-selective autophagy and mitochondrial homeostasis in human myeloid cells

    Elizabeth Rivers, Rajeev Rai ... Adrian J Thrasher
    WASp is an immunometabolic regulator of human myeloid cells and regulates autophagy and mitochondrial homeostasis.
    1. Chromosomes and Gene Expression

    Reassessment of the involvement of Snord115 in the serotonin 2c receptor pathway in a genetically relevant mouse model

    Jade Hebras, Virginie Marty ... Jérôme Cavaille
    Knockout of Snord115 has mild impact on expression and function of the serotonin 2C receptor.
    1. Neuroscience

    Emergence of non-canonical parvalbumin-containing interneurons in hippocampus of a murine model of type I lissencephaly

    Tyler G Ekins, Vivek Mahadevan ... Chris J McBain
    An excess of novel non-canonical subtypes of parvalbumin+ interneurons in a mouse model of classical lissencephaly, which possess non-fast-spiking physiological properties, may contribute to network hyperexcitability common in this model.
    1. Genetics and Genomics

    Mutations primarily alter the inclusion of alternatively spliced exons

    Pablo Baeza-Centurion, Belén Miñana ... Ben Lehner
    Deep mutagenesis reveals that mutations rarely alter the inclusion of highly-included exons.
    1. Genetics and Genomics

    Genetic profiling of protein burden and nuclear export overload

    Reiko Kintaka, Koji Makanae ... Hisao Moriya
    A comprehensive analysis of yeast mutants has provided clues to understanding the physiological conditions caused by protein overexpression.
    1. Cancer Biology
    2. Chromosomes and Gene Expression

    A small protein encoded by a putative lncRNA regulates apoptosis and tumorigenicity in human colorectal cancer cells

    Xiao Ling Li, Lőrinc Pongor ... Ashish Lal
    Discovery and initial characterization of a conserved small protein translated from a transcript annotated as a human long non-coding RNA.
    1. Ecology

    Humans disrupt access to prey for large African carnivores

    Kirby L Mills, Nyeema C Harris
    The presence of humans induces behavioral modifications in many large carnivore and ungulate species, restructuring spatiotemporal relationships between African predators and their prey.