Browse our Research Articles

The strength of pattern completion during memory retrieval, indexed by hippocampal activity and cortical reinstatement, explains within- and across-individual variability in episodic memory in older adults.

Genetic analyses reveal that the loss of Lin28a causes axial shortening with mild skeletal transformations via decreased PRC1 at Hox genes, establishing a new pathway in the “Hox code.”.

T-bet suppresses the expression of immature NK cell-defining genes.

Quantitative analysis of behavior coupled with computational modeling reveal the set of circuit-level principles that underlie cerebellar-dependent motor learning in smooth pursuit eye movements of monkeys across timescales.

SIMR-1 acts downstream of the piRNA pathway to promote siRNA amplification by the Mutator complex and localizes to perinuclear foci distinct from Mutator foci, P granules and Z granules.

Fluorescent glutamate indicators distort the time course of neurotransmitter diffusion and uptake by competing with transporters, an important caveat to consider when using iGluSnFR and its analogs.

H-ABC leukodystrophy results in neurologic decline, hypomyelination and atrophy of the striatum and cerebellum and Tubb4a^D249N/D249Nmouse model recapitulates features of H-ABC disease, providing an important tool for therapeutic development.

Mitochondrial electron transport chain dysfunction triggers the integrated stress response due to an asparagine deficiency downstream of impaired NADH oxidation in proliferating myoblasts, but not in differentiated myotubes.

HLA class I-disease associations have been studied for decades; a new approach for investigating the underlying mechanism can overcome past problems with interpretation and help to understand the etiology of human diseases.

Crystallography together with electron-resonance spectroscopy, molecular-dynamics simulations, and transport measurements reveal the molecular details of protein conformational change, and how this change contributes to function in a CLC-type chloride/proton exchanger.