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Structure of the portal protein of a thermostable virus, determined in its capsid-bound state, reveals a molecular mechanism that prevents DNA slippage during genome packaging.

A library of the paired peptide/HLA multimers and artificial APCs allows for construction of a large database of class I-restricted peptides and cognate tumor-reactive TCR genes at an unprecedented scale.

Macaque monkeys temporally compress past experiences and use a forward-replay mechanism during judgment of temporal-order between episodes.

HpBARI is a protein secreted by a parasitic helminth, which binds to and blocks the IL-33 receptor, suppressing IL-33-dependent type 2 immune responses.

PKD2 (polycystin-2) channels are a major component of a flow-sensing signaling mechanism in endothelial cells that stimulates vasodilation and reduces blood pressure.

A combination of high-resolution microscopy and reverse genetics identified key components of the alveolin network playing an essential role in the assembly of subpellicular microtubules and conoid in Toxoplasma gondii..

In the developing kidney, secreted molecules of the R-spondin family control progenitor cell proliferation and nephron formation by permitting WNT/β-catenin signalling.

The tetraspanin CD81 uses its ectodomain to export CD19, and the interaction of the two proteins is dynamically regulated by B cell activation state.

Humans with mutations in the AIRE gene exhibit common autoantibodies targeting ovarian and intestinal antigens, including intestinal dysfunction-associated antibodies to enteroendocrine transcription factor RFX6.

Anatomical and physiological analyses identified an inhibitory interneuron that is an integral part of the rod bipolar cell pathway, the circuit for night vision, of the mammalian retina.