Laura E Kuil, Nynke Oosterhof ... Tjakko J van Ham
Embryonic and definitive macrophages require colony-stimulating factor 1 receptor, whereas non-hematopoietic metaphocytes that resemble macrophages do not, explaining the relative high numbers of putative macrophages in Csf1r-deficient zebrafish.
The global ensemble forecasting niche modelling of 11 vector competent triatomine species revealed climatic suitable regions outside their native distribution including the cosmopolitan vector Triatoma rubrofasciata.
Sudhir Gopal Tattikota, Bumsik Cho ... Norbert Perrimon
Single-cell RNA sequencing of Drosophila hemocytes in blood distinguishes various states within known blood cell types and implicates a novel role for fibroblast growth factor receptor signaling in inter-hemocyte crosstalk.
The superior colliculus reveals hallmarks of sophisticated visual computation, including selectivity, invariance, and stimulus-specific habituation to behaviorally relevant stimuli.
The neuromodulator acetylcholine contributes to state-dependent modulation of motor vigor and variability by direct action on songbird premotor cortex, bypassing basal ganglia circuitry.
Motile interstitial T cells in live zebrafish access a broad range of length-scales due to long-lived cell-intrinsic variation in speed, and a coupling between speed and directional persistence.
Rarity metrics reveal pervasive negative impacts of agricultural land use on soil invertebrate communities, whereas widely-used richness and diversity metrics underestimate the magnitude of these impacts.
Mounir El Maï, Marta Marzullo ... Miguel Godinho Ferreira
Telomere shortening with age promotes a switch from p53-dependent apoptosis to senescence prompted by tissue damage that triggers conflicting mTOR/AKT signalling, lower OxPhos defences and ROS, mitochondria dysfunction and senescence.