Andrés Jara-Oseguera, Katherine E Huffer, Kenton J Swartz
The TRPV1, TRPV2 and TRPV3 channels are gated on the cytosolic side of the pore, whereas structural changes in the ion selectivity filter associated with activation don't control cation access.
The flow of somatosensory information through the spinal dorsal horn is regulated by synaptic inhibition, which acts upon excitatory and inhibitory interneurons, but the former are especially prone to disinhibition.
Paola Bardetti, Sónia Marisa Castanheira ... José Pérez-Martín
Degradation of a mitotic inducer coordinates the transition of two successive cell cycle arrests during the infective process of a plant pathogenic fungus.
Maria R Stupnikov, Ying Yang ... Wellington V Cardoso
Notch ligands from the Delta and Jagged families have distinct roles in epithelial progenitor cell fate of extrapulmonary and intrapulmonary airways and differentially restrict expansion of the neuroendocrine microenvironment.
The ES6S region of the small subunit ribosome makes a place for the threading and secondary structure unwinding of mRNA, which regulates genome-wide translation.
Hannes Ruge, Theo AJ Schäfer ... Uta Wolfensteller
Ventro-lateral prefrontal cortex codes novel rules starting from their first-time implementation right after instruction while early consolidation is channeled through increasing cooperation with the anterior striatum.
The fruit fly estimates visual motion by incorporating ON-OFF asymmetric processing that only improves performance when stimuli have light-dark asymmetries matched to natural scenes.
Neutrophils are essential for itch in a mouse model of atopic dermatitis, and promote the transition from acute to chronic itch via induction of CXCL10/CXCR3 signaling.
