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The expansion of the anterior Drosophila CNS is driven by increased progenitor generation and prolonged proliferation, mediated by brain-restricted genes and the PRC2.

CMG helicase translocates with force while encircling duplex DNA, enabling two opposing CMG complexes at an origin to melt the duplex and switch to encircling separate single strands.

Delay-period activity of anterior piriform cortex is important for working memory tasks requiring active maintenance and encodes the maintained information.

Widespread, rapidly evolving disordered regions contain molecular features that are preserved over evolution and are associated with specific biological functions.

Fetus and trophoblast interplay to regulate fetal nutrient supply and, ultimately, affect healthy growth.

The capacity for symbiosis between photosynthetic microalgae and early diverging lineages fungi was demonstrated with microscopy and stable isotope exchange of carbon and nitrogen.

Immune stimulation from the microbiota prevents neurological damage associated with viral infection of the central nervous system.

The dynamic phosphorylation of autophagy component WIPI2B is critical to maintain autophagosome biogenesis in neurons, and ectopic expression of WIPI2B can restore rates of autophagosome biogenesis in aged neurons.

Hey together with LaminC continuously supervise nuclear organisation and differentiated enterocyte identity, a regulation that is lost upon ageing, resulting in loss of gut homeostasis.

Relion was used to solve structures of microtubules decorated with dynein microtubule-binding domains revealing that an axonemal dynein distorts the microtubule cross-sectional curvature.