Browse our Research Articles

Page 965 of 1,385
    1. Immunology and Inflammation
    2. Neuroscience

    Re-evaluation of neuronal P2X7 expression using novel mouse models and a P2X7-specific nanobody

    Karina Kaczmarek-Hajek, Jiong Zhang ... Annette Nicke
    A novel BAC transgenic mouse model reveals glial restriction of P2X7 expression in the central and peripheral nervous systems.
    1. Neuroscience
    2. Stem Cells and Regenerative Medicine

    The retromer complex safeguards against neural progenitor-derived tumorigenesis by regulating Notch receptor trafficking

    Bo Li, Chouin Wong ... Yan Song
    The retromer complex serves as a bomb squad to retrieve and disarm the potentially harmful pool of Notch receptors in a timely manner and thereby safeguards against brain tumor formation.
    1. Neuroscience

    Functional properties of stellate cells in medial entorhinal cortex layer II

    David C Rowland, Horst A Obenhaus ... May-Britt Moser
    Stellate cells in the medial entorhinal cortex are functionally heterogeneous but a substantial fraction are grid cells.
    1. Neuroscience

    Revealing a novel nociceptive network that links the subthalamic nucleus to pain processing

    Arnaud Pautrat, Marta Rolland ... Veronique Coizet
    The subthalamic nucleus is linked to a nociceptive network and involved in nociceptive processing and perception.
    1. Biochemistry and Chemical Biology

    Poly(ADP-ribose) polymerase 1 searches DNA via a ‘monkey bar’ mechanism

    Johannes Rudolph, Jyothi Mahadevan ... Karolin Luger
    By moving between DNA segments like a child swinging on monkey bars, poly(ADP-ribose) polymerase 1 explores possible DNA damage sites more effectively.
    1. Neuroscience

    BDNF-TrkB signaling in oxytocin neurons contributes to maternal behavior

    Kristen R Maynard, John W Hobbs ... Keri Martinowich
    Brain-derived neurotrophic factor signaling plays a causal role in female-typical social behavior and modulates oxytocin neuron gene expression.
    1. Chromosomes and Gene Expression
    2. Plant Biology

    Arabidopsis RNA processing factor SERRATE regulates the transcription of intronless genes

    Corinna Speth, Emese Xochitl Szabo ... Sascha Laubinger
    Arabidopsis RNA processing factor SERRATE associates with the chromatin of intronless genes, which are usually expressed at low levels, to enhance polymerase II association.
    1. Evolutionary Biology

    Fitness effects of altering gene expression noise in Saccharomyces cerevisiae

    Fabien Duveau, Andrea Hodgins-Davis ... Patricia J Wittkopp
    The impact of changing gene expression noise on fitness reveals beneficial or deleterious effects in a stable environment depending how close the average expression level is to the fitness optimum.
    1. Developmental Biology
    2. Neuroscience

    Ordered arrangement of dendrites within a C. elegans sensory nerve bundle

    Zhiqi Candice Yip, Maxwell G Heiman
    A nerve bundle is not simply a cable of wires, but has order within it.
    1. Developmental Biology
    2. Neuroscience

    MAP7 regulates axon morphogenesis by recruiting kinesin-1 to microtubules and modulating organelle transport

    Stephen R Tymanskyj, Benjamin H Yang ... Le Ma
    An under-studied microtubule-associated protein is found to regulate axon growth and branching by modulating microtubule-based organelle transport through its dual interactions with microtubules and the conventional kinesin motor.